ArticleEuropean child & adolescent psychiatry2017
Abnormal functional connectivity strength in patients with adolescent-onset schizophrenia: a resting-state fMRI study.
Article in European child & adolescent psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cognitive Brain Signatures of Youth With Early Onset and Relatives With Schizophrenia: Evidence From fMRI Meta-analyses.Schizophrenia bulletin · 2020Pooled it
- Abnormalities of intrinsic regional brain activity in first-episode and chronic schizophrenia: a meta-analysis of resting-state functional MRIJournal of psychiatry & neuroscience : JPN · 2020Pooled it
- Schizophrenia and Neurodevelopment: Insights From Connectome Perspective.Schizophrenia bulletin · 2025Review
- Altered temporal lobe connectivity is associated with psychotic symptoms in drug-naïve adolescent patients with first-episode schizophrenia.European child & adolescent psychiatry · 2025Article
- Diminished functional segregation and resilience are associated with symptomatic severity and cognitive impairments in schizophrenia: a large-scale study.General psychiatry · 2024Article
- Resting-state functional MRI study of conventional MRI-negative intractable epilepsy in children.Frontiers in human neuroscience · 2024Article
- Altered Coupling of Cerebral Blood Flow and Functional Connectivity Strength in First-Episode Schizophrenia Patients With Auditory Verbal Hallucinations.Frontiers in neuroscience · 2022Article
- Altered Coupling Between Resting-State Cerebral Blood Flow and Functional Connectivity Strength in Cervical Spondylotic Myelopathy Patients.Frontiers in neurology · 2021Article
- MRI Insights Into Adolescent Neurocircuitry-A Vision for the Future.Frontiers in human neuroscience · 2020Article
- Enhanced Prefrontal Regional Homogeneity and Its Correlations With Cognitive Dysfunction/Psychopathology in Patients With First-Diagnosed and Drug-Naive Schizophrenia.Frontiers in psychiatry · 2020Article
- Altered coupling of spontaneous brain activities and brain temperature in patients with adolescent-onset, first-episode, drug-naïve schizophrenia.Neuroradiology · 2019Article
- Resting-State Functional MRI Study: Connection Strength of Brain Networks in DR Patients.Neuropsychiatric disease and treatment · 2019Article
- Research Progress in Biological Studies of Schizophrenia in China in 2017.Shanghai archives of psychiatry · 2018Review
- Psychopathology and socioeconomic position: what can be done to break the vicious circle?European child & adolescent psychiatry · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Structural and functional abnormalities were reported in the brain of patients with adolescent-onset schizophrenia (AOS). However, evidence of abnormal functional connectivity of the brain in AOS patients is limited. Thus, we analyzed the resting-state functional magnetic resonance scans of 48 drug-naive AOS patients and 31 healthy controls to determine their functional connectivity strength (FCS) and examined if FCS abnormalities were correlated with clinical characteristics. Compared with healthy controls, AOS patients showed significantly increased FCS in the left cerebellum VI and right inferior frontal gyrus/insula. A positive correlation was observed between FCS values in the right inferior frontal gyrus/insula and general psychopathology scores of positive and negative syndrome scale. Results suggest that functional connectivity pattern is disrupted in drug-naive AOS patients. The FCS values in this abnormal region have potential for evaluating the disease severity.
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