ArticleLasers in medical science2017
Effectiveness of repeated photodynamic therapy in the elimination of intracanal Enterococcus faecalis biofilm: an in vitro study.
Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 42 citations in OpenAlex.
- Ex Vivo Analysis of the Antimicrobial Effect of Diode Laser and Sodium Hypochlorite onJournal of dental research, dental clinics, dental prospects · 2026Article
- MixedJournal of fungi (Basel, Switzerland) · 2025Article
- Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy againstJournal of Taibah University Medical Sciences · 2025Review
- Antimicrobial efficacy of methylene blue-functionalized graphene oxide-mediated photodynamic therapy againstJournal of Taibah University Medical Sciences · 2025Article
- New strategies to enhance antimicrobial photo-sonodynamic therapy based on nanosensitizers against bacterial infections.Folia microbiologica · 2025Review
- Antibacterial effect of 940 nm diode laser onDental research journal · 2024Article
- Emerging nanosonosensitizers augment sonodynamic-mediated antimicrobial therapies.Materials today. Bio · 2023Review
- Diode laser on excision of giant peripheral odontogenic myxoma: a rare case report and literature review.Lasers in medical science · 2023Review
- Photocatalytic CuInternational journal of nanomedicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study aimed to investigate the effectiveness of photodynamic therapy in the elimination of intracanal Enterococcus faecalis biofilm and to analyse how a repeated light irradiation, replenishment of oxygen and photosensitiser affect the results of the photodynamic disinfecting protocol. After chemomechanical preparation, 46 single-rooted human teeth were infected with a clinical strain of E. faecalis and incubated for a week in microaerobic conditions. The experimental procedures included groups of single application of photodynamic therapy, two cycles of PDT, irrigation with 5.25% NaOCl solution and negative and positive control. The number of residing bacterial colonies in the root canals was determined based on the CFU/ml method. In the group of preparations irrigated with NaOCl, bacterial colonies were not observed. A single PDT eliminated 45% of the initial CFU/ml. Repeated PDT eradicated 95% of the intracanal bacterial biofilm. Photodynamic therapy has a high potential for the elimination of E. faecalis biofilm. There is a safe therapeutic window where photoinduced disinfection can be used as an adjuvant to conventional endodontic treatment, which remains the most effective.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.