Evidence map›Paper›PMID 28185044›Full record

ArticleJournal of autism and developmental disorders2017

A Predictive Coding Account of Psychotic Symptoms in Autism Spectrum Disorder.

Gerrit I van Schalkwyk, Fred R Volkmar, Philip R Corlett

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. The Generative Adversarial Brain.Frontiers in artificial intelligence · 2019
    Article
  13. Autism and psychosis as diametrical disorders of embodiment.Evolution, medicine, and public health · 2019
    Article
  14. Article
  15. The Predictive Coding Account of Psychosis.Biological psychiatry · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gerrit I van SchalkwykChild Study Center, Yale University School of Medicine, New Haven, CT, USA. Gerrit.vanschalkwyk@yale.edu.
Fred R VolkmarChild Study Center, Yale University School of Medicine, New Haven, CT, USA.
Philip R CorlettDepartment of Psychiatry, Clinical Neuroscience Research Unit, Connecticut Mental Health Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT, 06510, USA.

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Pathophysiology of Auditory HallucinationsR01MH067073 · NIMH · YALE UNIVERSITY · PI CORLETT, PHILIP · 2003 to 2015
$3.0M
NCATS NIH HHS UL1 TR000142NIMH NIH HHS R01 MH067073
6 · The paper itself

Abstract

The co-occurrence of psychotic and autism spectrum disorder (ASD) symptoms represents an important clinical challenge. Here we consider this problem in the context of a computational psychiatry approach that has been applied to both conditions-predictive coding. Some symptoms of schizophrenia have been explained in terms of a failure of top-down predictions or an enhanced weighting of bottom-up prediction errors. Likewise, autism has been explained in terms of similar perturbations. We suggest that this theoretical overlap may explain overlapping symptomatology. Experimental evidence highlights meaningful distinctions and consistencies between these disorders. We hypothesize individuals with ASD may experience some degree of delusions without the presence of any additional impairment, but that hallucinations are likely indicative of a distinct process.

Indexed as

Schizophrenic PsychologyAutism Spectrum DisorderEgoHumansLanguageModels, PsychologicalSchizophreniaSocial BehaviorASD and psychosisASD and schizophreniaPredictive coding

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.