Evidence map›Paper›PMID 28185034›Full record

ArticleEuropean journal of epidemiology2017

Agricultural activities and the incidence of Parkinson's disease in the general French population.

Sofiane Kab, Johan Spinosi, Laura Chaperon, Aline Dugravot, Archana Singh-Manoux, Frédéric Moisan, Alexis Elbaz

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Risk Factors for Brain Health in Agricultural Work: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
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  5. Review
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  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Breaking barriers in Parkinson's care: the multidisciplinary team approach.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Dietary Interventions in Parkinson's Disease.Journal of Parkinson's disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sofiane KabUniversité Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM-U1018, Hôpital Paul Brousse, 16 avenue Paul Vaillant-Couturier, Villejuif, France.
Johan SpinosiSanté publique France, Direction santé travail, 94415, Saint-Maurice, France.
Laura ChaperonSanté publique France, Direction santé travail, 94415, Saint-Maurice, France.
Aline DugravotUniversité Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM-U1018, Hôpital Paul Brousse, 16 avenue Paul Vaillant-Couturier, Villejuif, France.
Archana Singh-ManouxUniversité Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM-U1018, Hôpital Paul Brousse, 16 avenue Paul Vaillant-Couturier, Villejuif, France.
Frédéric MoisanSanté publique France, Direction santé travail, 94415, Saint-Maurice, France.
Alexis ElbazUniversité Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM-U1018, Hôpital Paul Brousse, 16 avenue Paul Vaillant-Couturier, Villejuif, France. alexis.elbaz@inserm.fr.ORCID 0000-0001-9724-5490
Université Paris-Sud · FRUniversité Claude Bernard Lyon 1 · FRSanté Publique France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most studies on pesticides and Parkinson's disease (PD) focused on occupational exposure in farmers. Whether non-occupational exposure is associated with PD has been little explored. We investigated the association between agricultural characteristics and PD incidence in a French nationwide ecologic study. We hypothesized that persons living in regions with agricultural activities involving more intensive pesticide use would be at higher risk. We identified incident PD cases from French National Health Insurance databases (2010-2012). The proportion of land dedicated to 18 types of agricultural activities was defined at the canton of residence level. We examined the association between agricultural activities and PD age/sex-standardized incidence ratios using multivariable multilevel Poisson regression adjusted for smoking, deprivation index, density of neurologists, and rurality (proportion of agricultural land); we used a false discovery rate approach to correct for multiple comparisons and compute q-values. We also compared incidence in clusters of cantons with similar agricultural characteristics (k-means algorithm). We identified 69,010 incident PD cases. Rurality was associated with higher PD incidence (p < 0.001). Cantons with higher density of vineyards displayed the strongest association (RR

Indexed as

AgedAge DistributionAgricultureAgrochemicalsFemaleFranceHumansIncidenceMaleParkinson DiseasePesticidesRisk FactorsSex DistributionAgrochemicalsPesticidesAgricultureEpidemiologyIncidenceParkinson’s diseasePesticides

Identifiers

PMID28185034
OpenAlexW2587180143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.