Evidence map›Paper›PMID 28184992›Full record

ArticleRheumatology international2017

Association study between the TP53 Rs1042522G/C polymorphism and susceptibility to systemic lupus erythematosus in a Chinese Han population.

Jie Yang, Ji-Min Zhu, Song Wu, Jing Li, Ming-Rui Wang, Ting-Ting Wang, Yu-Wei Lu

Abstract read
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Article in Rheumatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie YangDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.ORCID http://orcid.org/0000-0001-5583-5062
Ji-Min ZhuDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.
Song WuDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.
Jing LiDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.
Ming-Rui WangDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.
Ting-Ting WangDepartment of Public Health and General Medicine, School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, 103 Meishan Road Hefei, Anhui, 230038, China.
Yu-Wei LuDepartment of Information, The Second Hospital of Anhui Medical University, 678 Furong Road Hefei, Anhui, 230601, China. 21655673@qq.com.ORCID http://orcid.org/0000-0002-3461-2238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour suppressor protein 53 (p53) plays a central role in apoptosis, cell proliferation and death. Previously studies found contribution of functional p53 Arg72Pro polymorphism (TP53 rs1042522G/C polymorphism) in the development of systemic lupus erythematosus (SLE) remains controversial. In this study, for the first time, we evaluated its association with SLE in a Chinese Han population. This case-control study enrolled 1470 SLE patients and 2283 healthy controls. The genotyping of TP53 rs1042522 polymorphism was determined by Sequenom Mass ARRAY technology. Statistical analysis was conducted by Chi-square test (χ

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAdolescentAdultAgedAllelesAsian PeopleCase-Control StudiesChinaFemaleGene FrequencyGenotypeHumansLupus Erythematosus, SystemicMaleMiddle AgedTP53 protein, humanTumor Suppressor Protein p53Case-control studyP53Systemic lupus erythematosusTP53 rs1042522G/C polymorphism

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.