ArticleCerebral cortex (New York, N.Y. : 1991)2017
Body Topography Parcellates Human Sensory and Motor Cortex.
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed.
- Functional harmonics reveal multi-dimensional basis functions underlying cortical organization.Cell reports · 2021Trial
- Spatial and Functional Organization of the Somato-Cognitive Action Network During Cue and Execution of Motor Tasks.Research square · 2026Article
- Article
- The In Vivo Microstructural Profile of Human Hippocampal Subfield CA1 and Its Relation to Memory Performance.Human brain mapping · 2026Article
- Parallel processing chains span cytoarchitectures to organize association cortex.bioRxiv : the preprint server for biology · 2026Article
- Layer-specific attentional modulation in the human primary somatosensory cortex.Nature communications · 2026Article
- Article
- Individualized phenotyping of functional amyotrophic lateral sclerosis pathology in sensorimotor cortex.Brain communications · 2026Article
- Functional organization of the primary motor cortex in psychosis and the potential role of intereffector regions in psychomotor slowing.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Layer-specific changes in sensory cortex across the lifespan in mice and humans.Nature neuroscience · 2025Article
- Investigating age-related decline in sensorimotor control using robotic tasks.Frontiers in aging neuroscience · 2025Article
- Multimodal layer modelling reveals in vivo pathology in amyotrophic lateral sclerosis.Brain : a journal of neurology · 2024Article
- Age-related differences in human cortical microstructure depend on the distance to the nearest vein.Brain communications · 2024Article
- Similar somatotopy for active and passive digit representation in primary somatosensory cortex.Human brain mapping · 2023Article
- The 3D Structural Architecture of the Human Hand Area Is Nontopographic.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Article
- Transcriptional substrates underlying functional connectivity profiles of subregions within the human sensorimotor cortex.Human brain mapping · 2022Article
- Spatial probability maps of the segments of the postcentral sulcus in the human brain.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Development of functional organization within the sensorimotor network across the perinatal period.Human brain mapping · 2022Article
- Beyond body maps: Information content of specific body parts is distributed across the somatosensory homunculus.Cell reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The cytoarchitectonic map as proposed by Brodmann currently dominates models of human sensorimotor cortical structure, function, and plasticity. According to this model, primary motor cortex, area 4, and primary somatosensory cortex, area 3b, are homogenous areas, with the major division lying between the two. Accumulating empirical and theoretical evidence, however, has begun to question the validity of the Brodmann map for various cortical areas. Here, we combined in vivo cortical myelin mapping with functional connectivity analyses and topographic mapping techniques to reassess the validity of the Brodmann map in human primary sensorimotor cortex. We provide empirical evidence that area 4 and area 3b are not homogenous, but are subdivided into distinct cortical fields, each representing a major body part (the hand and the face). Myelin reductions at the hand-face borders are cortical layer-specific, and coincide with intrinsic functional connectivity borders as defined using large-scale resting state analyses. Our data extend the Brodmann model in human sensorimotor cortex and suggest that body parts are an important organizing principle, similar to the distinction between sensory and motor processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.