Evidence map›Paper›PMID 28184245›Full record

ArticleBiotechnology for biofuels2017

Development of a low-cost cellulase production process using

Simo Ellilä, Lucas Fonseca, Cristiane Uchima, Junio Cota, Gustavo Henrique Goldman, Markku Saloheimo, Vera Sacon, Matti Siika-Aho

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 270 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Robust Production of Cellulases to Develop a Low-Cost Sugar Platform.Advances in biochemical engineering/biotechnology · 2026
    Review
  5. Article
  6. Cellulase Production by Ultraviolet-Derived MutantInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Development of a High-PerformanceJournal of fungi (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Biofunctionalization of Magneto-Plasmonic FeMolecules (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Simo ElliläVTT Brasil Ltda., Barueri, Sao Paulo Brazil.ORCID 0000-0001-7516-3363
Lucas FonsecaVTT Brasil Ltda., Barueri, Sao Paulo Brazil.
Cristiane UchimaVTT Brasil Ltda., Barueri, Sao Paulo Brazil.
Junio CotaVTT Brasil Ltda., Barueri, Sao Paulo Brazil.
Gustavo Henrique GoldmanFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de Sao Paulo, Ribeirão Preto, SP Brazil.
Markku SaloheimoVTT Technical Research Centre of Finland, Tietotie 2, 02044 Espoo, Finland.
Vera SaconVTT Brasil Ltda., Barueri, Sao Paulo Brazil.
Matti Siika-AhoVTT Technical Research Centre of Finland, Tietotie 2, 02044 Espoo, Finland.
AES (Brazil) · BRTieto (Finland) · FIUniversidade de Ribeirão Preto · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the past few years, the first industrial-scale cellulosic ethanol plants have been inaugurated. Although the performance of the commercial cellulase enzymes used in this process has greatly improved over the past decade, cellulases still represent a very significant operational cost. Depending on the region, transport of cellulases from a central production facility to a biorefinery may significantly add to enzyme cost. The aim of the present study was to develop a simple, cost-efficient cellulase production process that could be employed locally at a Brazilian sugarcane biorefinery.

resultsOur work focused on two main topics: growth medium formulation and strain improvement. We evaluated several Brazilian low-cost industrial residues for their potential in cellulase production. Among the solid residues evaluated, soybean hulls were found to display clearly the most desirable characteristics. We engineered a

conclusionsIn this study, we showed that with relatively few genetic modifications and the right growth medium it is possible to produce considerable amounts of well-performing cellulase at very low cost in Brazil using

Indexed as

BiorefineryBrazilCellulaseCellulosic ethanolEnzymeMolassesOn-siteSoybean hullsSugarcaneTrichoderma reesei

Identifiers

PMID28184245
PMCPMC5289010
OpenAlexW2583248807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.