Evidence map›Paper›PMID 28184163›Full record

ArticleInternational journal of nanomedicine2017

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile.

Pedram Rafiei, Azita Haddadi

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 1 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 1 synthesis or guideline pooled it, 284 citations in OpenAlex.

  1. Pooled it
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  14. Development of Polymeric Nanoparticles Loaded withInternational journal of molecular sciences · 2025
    Article
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  18. RSC advances · 2024
    Article
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50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pedram RafieiDivision of Pharmacy, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada.
Azita HaddadiDivision of Pharmacy, College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada.
University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer types. There are important matters of concern regarding the drug's pharmacokinetics related to the conventional formulation. Poly(lactide-

Indexed as

Drug Delivery SystemsAnimalsAntineoplastic AgentsChemistry, PharmaceuticalDocetaxelDrug CarriersFemaleHumansLactic AcidMiceMice, Inbred BALB CNanoparticlesParticle SizePolyethylene GlycolsPolyglactin 910Polyglycolic AcidAntineoplastic AgentsDocetaxelDrug CarriersLactic AcidPolyethylene GlycolsPolyglactin 910Polyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerpoly(lactic-glycolic acid)-poly(ethyleneglycol) copolymerTaxoidsbiodistributiondocetaxelemulsification solvent evaporationpharmacokineticspoly(lactide-co-glycolide)poly(lactide-co-glycolide)-poly(ethylene glycol)polymeric nanoparticlessustained release

Identifiers

PMID28184163
PMCPMC5291330
OpenAlexW2582481970

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.