Evidence map›Paper›PMID 28183993›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

Multiparametric Imaging of Tumor Hypoxia and Perfusion with

Milan Grkovski, Heiko Schöder, Nancy Y Lee, Sean D Carlin, Bradley J Beattie, Nadeem Riaz, Jonathan E Leeman, Joseph A O'Donoghue, John L Humm

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Randomized Phase II Study of Physiologic MRI-Directed Adaptive Radiation Boost in Poor Prognosis Head and Neck Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Trial
  3. Prospective Evaluation of a Tumor Control Probability Model Based on DynamicJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Trial
  4. Monitoring early response to chemoradiotherapy withEuropean journal of nuclear medicine and molecular imaging · 2017
    Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. [Asia Oceania journal of nuclear medicine & biology · 2025
    Article
  11. Review
  12. Article
  13. Sononeoperfusion: a new therapeutic effect to enhance tumour blood perfusion using diagnostic ultrasound and microbubbles.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  14. Kinetic Evaluation of the Hypoxia Radiotracers [Nuclear medicine and molecular imaging · 2023
    Article
  15. Oxygenation imaging in deep tissue with X-Ray luminescence computed tomography (XLCT).Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  16. The optimalEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Milan GrkovskiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York grkovskm@mkscc.org.
Heiko SchöderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Nancy Y LeeDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Sean D CarlinDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Bradley J BeattieDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Nadeem RiazDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Jonathan E LeemanDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Joseph A O'DonoghueDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
John L HummDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Dose de-escalation of HPV-associated oropharynx cancers: Exploration of HPV mediated radiation sensitivityR01CA238392 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Nancy Y Lee · 2020 to 2026
$5.5M
Hypoxia Image-Guided Radiation TherapyR01CA157770 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEE, NANCY Y · 2012 to 2016
$2.1M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA157770NCI NIH HHS R01 CA238392
6 · The paper itself

Abstract

Tumor hypoxia and perfusion are independent prognostic indicators of patient outcome. We developed the methodology for and investigated the utility of multiparametric imaging of tumor hypoxia and perfusion with

Indexed as

AdultAgedAged, 80 and overFemaleHead and Neck NeoplasmsHumansImage Interpretation, Computer-AssistedMaleMiddle AgedMisonidazoleMultimodal ImagingNeovascularization, PathologicObserver VariationOxygenPerfusion ImagingPositron-Emission TomographyfluoromisonidazoleMisonidazoleOxygenRadiopharmaceuticals18F-fluoromisonidazoledynamic PETFMISOhead and neck cancerhypoxiaperfusion

Identifiers

PMID28183993
PMCPMC5493008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.