ArticlePhysiological reports2017
The mechanisms underlying the muscle metaboreflex modulation of sweating and cutaneous blood flow in passively heated humans.
Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Purinergic signaling as a new mechanism underlying physical exercise benefits: a narrative review.Purinergic signalling · 2021Review
- β-Adrenergic receptor blockade does not modify non-thermal sweating during static exercise and following muscle ischemia in habitually trained individuals.European journal of applied physiology · 2018Article
- Do nitric oxide synthase and cyclooxygenase contribute to sweating response during passive heating in endurance-trained athletes?Physiological reports · 2017Article
- The mechanisms underlying the muscle metaboreflex modulation of sweating and cutaneous blood flow in passively heated humans.Physiological reports · 2017Article
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Authors and funding
4 authors.
Funding
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Abstract
Metaboreceptors can modulate cutaneous blood flow and sweating during heat stress but the mechanisms remain unknown. Fourteen participants (31 ± 13 years) performed 1-min bout of isometric handgrip (IHG) exercise at 60% of their maximal voluntary contraction followed by a 3-min occlusion (OCC), each separated by 10 min, initially under low (LHS, to activate sweating without changes in core temperature) and high (HHS, whole-body heating to a core temperature increase of 1.0°C) heat stress conditions. Cutaneous vascular conductance (CVC) and sweat rate were measured continuously at four forearm skin sites perfused with 1) lactated Ringer's solution (Control), 2) 10 mmol L-NAME [inhibits nitric oxide synthase (NOS)], 3) 10 mmol Ketorolac [inhibits cyclooxygenase (COX)], or 4) 4 mmol theophylline (THEO; inhibits adenosine receptors). Relative to pre-IHG levels with Control, NOS inhibition attenuated the metaboreceptor-mediated increase in sweating under LHS and HHS (
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