ArticleMetabolism: clinical and experimental2017
Antecedent longitudinal changes in body mass index are associated with diurnal cortisol curve features: The multi-ethnic study of atherosclerosis.
Article in Metabolism: clinical and experimental, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Optimal dose of maintenance steroid therapy for relapse of chronic eosinophilic pneumonia: a multicentre retrospective study.BMJ open respiratory research · 2025Article
- Serum Cortisol and Cardiovascular Disease Risk - A Potential Biomarker.Current cardiology reviews · 2025Review
- Brain Dopamine-Clock Interactions Regulate Cardiometabolic Physiology: Mechanisms of the Observed Cardioprotective Effects of Circadian-Timed Bromocriptine-QR Therapy in Type 2 Diabetes Subjects.International journal of molecular sciences · 2023Review
- Cortisol and cardiometabolic disease: a target for advancing health equity.Trends in endocrinology and metabolism: TEM · 2022Review
- Adiposity Measures and Morning Serum Cortisol in African Americans: Jackson Heart Study.Obesity (Silver Spring, Md.) · 2021Article
- The longitudinal association of changes in diurnal cortisol features with fasting glucose: MESA.Psychoneuroendocrinology · 2020Article
- Association of generalized and central obesity with serum and salivary cortisol secretion patterns in the elderly: findings from the cross sectional KORA-Age study.Scientific reports · 2020Article
- Predictors of Obesity among Gut Microbiota Biomarkers in African American Men with and without Diabetes.Microorganisms · 2019Article
- The association of morning serum cortisol with glucose metabolism and diabetes: The Jackson Heart Study.Psychoneuroendocrinology · 2019Article
- Longitudinal Associations of Sleep Duration, Morning and Evening Cortisol, and BMI During Childhood.Obesity (Silver Spring, Md.) · 2019Article
- IN MY OWN WORDS: THE VALUE OF STORYTELLING TO SHAPE THE ACADEMIC MEDICINE JOURNEY.Transactions of the American Clinical and Climatological Association · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
contextPrior studies have shown a cross-sectional association between body mass index (BMI) and salivary diurnal cortisol profile features (cortisol features); however, to our knowledge prior population-based studies have not examined the longitudinal association of body-mass index (BMI) with cortisol features.
objectiveTo examine the association of (1) prior annual BMI percent change over 7years with cortisol features, (2) baseline cortisol features with subsequent change in BMI over 6years and (3) the association of change in cortisol features with change in BMI over 6years.
designLongitudinal study.
settingMulti-Ethnic Study of Atherosclerosis (MESA) Stress I & II Studies (2004-2006 & 2010-2012).
participants1685 ethnically diverse men and women attended either MESA Stress exam (mean age 65±10years at MESA Stress I; mean age 69±9years at MESA Stress II). OUTCOME MEASURES: Log-transformed cortisol features including wake-up cortisol, cortisol awakening response, early decline slope (30min to 2h post-awakening), late decline slope (2h post-awakening to bedtime), bedtime, and total area under the curve (AUC) cortisol.
resultsOver 7years, following multivariable adjustment, (1) a 1% higher prior annual BMI % increase was associated with a 2.9% (95% CI: -5.0%, -0.8%) and 3.0% (95% CI: -4.7%, -1.4%) lower current wake-up and total AUC cortisol, respectively; (2) there was no significant association between baseline cortisol features and subsequent change in BMI and (3) among participants with BMI≥30kg/m
conclusionsWe found a significant association between prior annual BMI % change and cortisol features, but no significant association between baseline cortisol features and subsequent change in BMI. In participants with obesity increases in BMI were associated with less pronounced declined. Collectively, our results suggest that greater adiposity may lead to a blunted diurnal cortisol profile.
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