Evidence map›Paper›PMID 28183322›Full record

Trial reportTrials2017

Impact of a pharmacist-led medication review on hospital readmission in a pediatric and elderly population: study protocol for a randomized open-label controlled trial.

Pierre Renaudin, Karine Baumstarck, Aurélie Daumas, Marie-Anne Esteve, Stéphane Gayet, Pascal Auquier, Michel Tsimaratos, Patrick Villani, Stéphane Honore

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02734017 (Impact of a Medication Review on Hospital Readmission), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02734017 naterminatednot on this map

Impact of a Medication Review on Hospital Readmission: Study Protocol of a Randomized Controlled Trial

TypeinterventionalSponsorAssistance Publique Hopitaux De MarseilleRan2016 to 2019Enrolled470ConditionsRe-hospitalizationArmspharmacist-led standardized medication review
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Development of a Discharge Counseling and Medication Reconciliation Process for Pediatric Patients Within a Large, Academic Health System.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pierre RenaudinHôpitaux de Marseille, Hôpital La Timone, Service Pharmacie, Marseille, F-13000, France. renaudin.pierre@ap-hm.fr.
Karine BaumstarckHôpitaux de Marseille, Hôpital La Timone, Unité d'Aide Méthodologique à la Recherche Clinique et Epidémiologique, Marseille, F-13000, France.
Aurélie DaumasHôpitaux de Marseille, Hôpital La Timone, Service de Médecine Interne, Gériatrie et Thérapeutique, Marseille, F-13000, France.
Marie-Anne EsteveHôpitaux de Marseille, Hôpital La Timone, Service Pharmacie, Marseille, F-13000, France.
Stéphane GayetHôpitaux de Marseille, Hôpital La Timone, Service de Médecine Interne, Gériatrie et Thérapeutique, Marseille, F-13000, France.
Pascal AuquierHôpitaux de Marseille, Hôpital La Timone, Unité d'Aide Méthodologique à la Recherche Clinique et Epidémiologique, Marseille, F-13000, France.
Michel TsimaratosHôpitaux de Marseille, Hôpital La Timone, Service de Pédiatrie Multidisciplinaire, Marseille, F-13000, France.
Patrick VillaniHôpitaux de Marseille, Hôpital La Timone, Service de Médecine Interne, Gériatrie et Thérapeutique, Marseille, F-13000, France.
Stéphane HonoreHôpitaux de Marseille, Hôpital La Timone, Service Pharmacie, Marseille, F-13000, France.
Hôpital de la Timone · FRAssistance Publique Hôpitaux de Marseille · FRCentre de Recherche en Cancérologie de Marseille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly hospital readmission of patients after discharge is a public health problem. One major cause of hospital readmission is dysfunctions in integrated pathways between community and hospital care that can cause adverse drug events. Furthermore, the French ENEIS 2 study showed that 1.3% of hospital stays originated from serious adverse drug events in 2009. Pharmacy-led medication reviews at hospital transitions are an effective means of decreasing medication discrepancies when conducted at admission or discharge. However, it is difficult to assess the true impact of pharmacist-led medication reviews in specific high-risk populations, such as pediatric and geriatric populations. In such a context, it is important to demonstrate the effectiveness of medication reconciliation as part of a standardized medication review process-in pediatric and elderly populations-on all-cause readmissions in a large randomized controlled clinical trial. The aim of this study is to assess the impact of the pharmacist-led medication review on the rate of readmissions and/or death after hospital discharge and patient treatment satisfaction. METHODS/

designThe study is a randomized controlled clinical trial. A total of 1400 hospitalized patients will be randomized in two groups: (1) the experimental group (group receiving a pharmacist-led medication review) and (2) the control group (group receiving usual care). The pharmacist-led medication review process includes medication reconciliation, treatment review and medication liaison service. The primary endpoint will be the rate of readmissions and/or death at 30 days following initial hospitalization discharge. The secondary endpoints will be the rate of hospital readmission, the rate of emergency department visits, the rate of mortality, the number of consultations and patient treatment satisfaction at 30 days following initial hospitalization discharge. DISCUSSION: A randomized controlled trial provides the most extensive evidence on the impact of pharmacist-led medication reviews on early hospital readmission for extreme age populations.

trial registrationCurrent Controlled Trials, NCT02734017 . Registered on 4 May 2016.

Indexed as

InpatientsMedication ReconciliationMedication Therapy ManagementPatient ReadmissionPharmacistsPharmacy Service, HospitalProfessional RoleAdolescentAgedAge FactorsCause of DeathChildClinical ProtocolsEmergency Service, HospitalFemaleFranceClinical pharmacyGeriatricsMedication reconciliationMedication reviewPediatricsPharmacistsRandomized controlled trial

Identifiers

PMID28183322
PMCPMC5301437
OpenAlexW2587378572

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.