Evidence map›Paper›PMID 28182905›Full record

ReviewNeuron2017

Cracking the Neural Code for Sensory Perception by Combining Statistics, Intervention, and Behavior.

Stefano Panzeri, Christopher D Harvey, Eugenio Piasini, Peter E Latham, Tommaso Fellin

Abstract readReview
In one paragraph

Review in Neuron, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Spatiotemporal Divergence Between Intrinsic And Evoked Cortical Activity Predicts Visual Detection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  5. Review
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  8. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Survey of temporal coding of sensory information.Frontiers in computational neuroscience · 2025
    Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefano PanzeriNeural Computation Laboratory, Istituto Italiano di Tecnologia, 38068 Rovereto, Italy; Neural Coding Laboratory, Istituto Italiano di Tecnologia, 38068 Rovereto, Italy. Electronic address: stefano.panzeri@iit.it.
Christopher D HarveyDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: christopher_harvey@hms.harvard.edu.
Eugenio PiasiniNeural Computation Laboratory, Istituto Italiano di Tecnologia, 38068 Rovereto, Italy.
Peter E LathamGatsby Computational Neuroscience Unit, University College London, London, W1T 4JG, UK.
Tommaso FellinNeural Coding Laboratory, Istituto Italiano di Tecnologia, 38068 Rovereto, Italy; Optical Approaches to Brain Function Laboratory, Istituto Italiano di Tecnologia, 16163 Genoa, Italy. Electronic address: tommaso.fellin@iit.it.

Funding

Parietal Cortex Networks for Sensorimotor Processing During NavigationR01NS089521 · NINDS · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2015 to 2024
$4.5M
New approaches to understand neuronal microcircuit dynamics for working memoryR01MH107620 · NIMH · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2015 to 2019
$2.8M
The role of patterned activity in neuronal codes for behaviorU01NS090576 · NINDS · UNIVERSITY OF CHICAGO · PI FELLIN, TOMMASO, HISTED, MARK H · 2014 to 2016
$1.6M
NIMH NIH HHS R01 MH107620NINDS NIH HHS R01 NS089521NINDS NIH HHS U01 NS090576Wellcome Trust
6 · The paper itself

Abstract

The two basic processes underlying perceptual decisions-how neural responses encode stimuli, and how they inform behavioral choices-have mainly been studied separately. Thus, although many spatiotemporal features of neural population activity, or "neural codes," have been shown to carry sensory information, it is often unknown whether the brain uses these features for perception. To address this issue, we propose a new framework centered on redefining the neural code as the neural features that carry sensory information used by the animal to drive appropriate behavior; that is, the features that have an intersection between sensory and choice information. We show how this framework leads to a new statistical analysis of neural activity recorded during behavior that can identify such neural codes, and we discuss how to combine intersection-based analysis of neural recordings with intervention on neural activity to determine definitively whether specific neural activity features are involved in a task.

Indexed as

OptogeneticsStatistics as TopicAnimalsBehavior, AnimalBrainChoice BehaviorPerceptionbehaviorchoiceinformationneural codingoptogeneticspopulation coding

Identifiers

PMID28182905
PMCPMC5308795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.