Evidence map›Paper›PMID 28182850›Full record

ArticleChembiochem : a European journal of chemical biology2017

Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look.

Peng Xu, Meagan Kelly, Willie F Vann, Firdausi Qadri, Edward T Ryan, Pavol Kováč

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Virus-like Particle Display ofACS infectious diseases · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cholera: Immunity and Prospects in Vaccine Development.The Journal of infectious diseases · 2018
    Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Peng XuNIDDK, LBC, Section on Carbohydrates, National Institutes of Health (NIH), Bethesda, MD, 20892-0815, USA.ORCID 0000-0002-1867-0059
Meagan KellyDepartment of Immunology and Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
Willie F VannLaboratory of Bacterial Toxins, CBER, FDA, Silver Spring, MD, 20993, USA.
Firdausi QadriInternational Centre for Diarrhoeal Disease Research Bangladesh, icddr, b), Dhaka, Bangladesh.
Edward T RyanDepartment of Immunology and Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.
Pavol KováčNIDDK, LBC, Section on Carbohydrates, National Institutes of Health (NIH), Bethesda, MD, 20892-0815, USA.ORCID 0000-0001-5044-3449
National Institutes of Health · USCenter for Biologics Evaluation and Research · USInternational Centre for Diarrhoeal Disease Research · BDMassachusetts Department of Public Health · USMassachusetts General Hospital · US

Funding

Reactions And Immunochemistry Of CarbohydratesZIADK059701 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOVAC, PAVOL · 2009 to 2019
$9.5M
O-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1M
O-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7M
REACTIONS AND IMMUNOCHEMISTRY OF CARBOHYDRATESZ01DK059701 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI KOVAC, PAVOL · 1991 to 2008
$1.5M
Intramural NIH HHS Z01 DK059701NIAID NIH HHS R01 AI106878NIAID NIH HHS R37 AI106878
6 · The paper itself

Abstract

By using O-SP-core (O-SPcNH

Indexed as

AnimalsAntigens, BacterialCattleCholeraCholera VaccinesCyclobutanesGlycoconjugatesHumansHydrogen-Ion ConcentrationMicePeptide FragmentsSerum Albumin, BovineTetanus ToxinTyphoid FeverVaccines, ConjugateVibrio choleraeAntigens, BacterialCholera VaccinesCyclobutanesGlycoconjugatesPeptide FragmentsSerum Albumin, Bovinesquaric acidTetanus Toxintetanus toxin fragment CVaccines, ConjugateantigensglycoconjugatesO-specific polysaccharidesselective methylationvaccines

Identifiers

PMID28182850
PMCPMC5664186
OpenAlexW2586527943

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.