Evidence map›Paper›PMID 28182800›Full record

ArticleJournal of hospital medicine2017

Cost of Acute Kidney Injury in Hospitalized Patients.

Samuel A Silver, Jin Long, Yuanchao Zheng, Glenn M Chertow

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of hospital medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
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  8. Preoperative serum ST2 level predicts acute kidney injury after adult cardiac surgery.The Journal of thoracic and cardiovascular surgery · 2018
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  18. Beyond the budget impact model: A case study for glucarpidase and the real cost of managing curable toxicities.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2025
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  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Samuel A SilverDivision of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA.
Jin LongDivision of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA.
Yuanchao ZhengDivision of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA.
Glenn M ChertowDivision of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA.

Funding

Mentoring Patient-Oriented Clinical Investigators in NephrologyK24DK085446 · NIDDK · STANFORD UNIVERSITY · PI CHERTOW, GLENN MATTHEW · 2010 to 2022
$1.4M
CIHRNIDDK NIH HHS K24 DK085446
6 · The paper itself

Abstract

backgroundThe economic burden of acute kidney injury (AKI) is not well understood.

objectiveTo estimate the effects of AKI on hospitalization costs and length of stay (LOS).

designUsing data from the 2012 National Inpatient Sample, we compared hospitalization costs and LOS with and without AKI. We used a generalized linear model with a gamma distribution and a log link fitted to AKI to adjust for demographics, hospital differences, and comorbidities.

settingUnited States. PATIENTS: 29,763,649 adult hospitalizations without endstage renal disease. EXPOSURE: AKI determined using International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) diagnosis codes.. MEASUREMENTS: Hospitalization costs and LOS.

resultsAKI was associated with an increase in hospitalization costs of $7933 (95% confidence interval [CI], $7608-$8258) and an increase in LOS of 3.2 (95% CI, 3.2-3.3) days compared to patients without AKI. When adjusted for patient and hospital characteristics, the associated increase in costs was $1795 (95% CI, $1692-$1899) and in LOS, it was 1.1 (95% CI, 1.1-1.1) days. Corresponding results among patients hospitalized with AKI requiring dialysis were $42,077 (95% CI, $39,820-$44,335) and 11.5 (95% CI, 11.2-11.8) days and $11,016 (95% CI, $10,468-$11,564) and 3.9 (95% CI, 3.8-4.1) days. AKI was associated with higher hospitalization costs than myocardial infarction and gastrointestinal bleeding, and costs were comparable to those for stroke, pancreatitis, and pneumonia..

conclusionsIn the United States, AKI is associated with excess hospitalization costs and prolonged LOS. The economic burden of AKI warrants further attention from hospitals and policymakers to enhance processes of care and develop novel treatment strategies. Journal of Hospital Medicine 2017;12:70-76.

Indexed as

InpatientsAcute Kidney InjuryAgedComorbidityCost of IllnessFemaleHospital CostsHospitalizationHumansLength of StayMaleMiddle AgedSurveys and QuestionnairesUnited States

Identifiers

PMID28182800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.