ArticlePloS one2017
IGF-I and relation to growth in infancy and early childhood in very-low-birth-weight infants and term born infants.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pooled it
- Glucose-regulatory hormones and growth in very preterm infants fed fortified human milk.Pediatric research · 2024Trial
- Better growth outcomes in GH-deficient children treated younger than 2 years of age.Endocrine connections · 2025Article
- The Possible Role of Postnatal Biphasic Dysregulation of IGF-1 Tone in the Etiology of Idiopathic Autism Spectrum Disorder.International journal of molecular sciences · 2025Review
- Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 as early predictors of growth, body composition, and neurodevelopment in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Gut development following insulin-like growth factor-1 supplementation to preterm pigs.Pediatric research · 2024Article
- Correlations of Aflatoxin Exposure from Cooking Oil and Dietary Foods During Pregnancy with Birth Weight and Gestational Age at Birth in Guangxi, China.International journal of general medicine · 2024Article
- Article
- Neighborhood Social Vulnerability and Interstage Weight Gain: Evaluating the Role of a Home Monitoring Program.Journal of the American Heart Association · 2023Article
- Correction of neonatal vitamin D status using 1000 IU vitamin D/d increased lean body mass by 12 months of age compared with 400 IU/d: a randomized controlled trial.The American journal of clinical nutrition · 2022Article
- Clinical outcome and gut development after insulin-like growth factor-1 supplementation to preterm pigs.Frontiers in pediatrics · 2022Article
- An integrated approach to identify environmental modulators of genetic risk factors for complex traits.American journal of human genetics · 2021Article
- RELATIONSHIP BETWEEN INSULIN-LIKE GROWTH FACTOR TYPE 1 AND INTRAUTERINE GROWTH.Acta clinica Croatica · 2020Article
- Effect of Early Breast Milk Nutrition on Serum Insulin-Like Growth Factor-1 in Preterm Infants.Open access Macedonian journal of medical sciences · 2019Article
- Insulin-Like Growth Factor-1 Is Neuroprotective in Aged Rats With Ischemic Stroke.Frontiers in aging neuroscience · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn very-low-birth-weight infants IGF-I plays an important role in postnatal growth restriction and is probably also involved in growth restriction in childhood. We compared IGF-I and its relation to growth in early childhood in very-low-birth-weight infants and term appropriate for gestational age born infants.
methodsWe included 41 very-low-birth-weight and 64 term infants. Anthropometry was performed at all visits to the outpatient clinic. IGF-I and insulin were measured in blood samples taken at 6 months and 2 years corrected age (very-low-birth-weight children) and at 3 months, 1 and 2 years (term children).
resultsOver the first 2 years of life growth parameters are lower in very-low-birth-weight children compared to term children, but the difference in length decreases significantly. During the first 2 years of life IGF-I is higher in very-low-birth-weight children compared to term children. In both groups there is a significant relationship between IGF-I and (change in) length and weight over the first 2 years of life and between insulin and change in total body fat.
conclusionsConsidering the relation of IGF-I to growth and the decrease in difference in length, higher IGF-I levels in very-low-birth-weight infants in early childhood probably have an important role in catch-up growth in length.
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