ArticlePloS one2017
Multi-locus genotypes of Enterocytozoon bieneusi in captive Asiatic black bears in southwestern China: High genetic diversity, broad host range, and zoonotic potential.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of microsporidia in China : A systematic review and meta-analysis.Scientific reports · 2019Pooled it
- Occurrence and Multi-Locus Genotyping ofPathogens (Basel, Switzerland) · 2026Article
- Molecular evidence of host range expansion ofOne health (Amsterdam, Netherlands) · 2025Article
- Occurrence and Molecular Characteristics of Microsporidia in Captive Red Pandas (Animals : an open access journal from MDPI · 2023Article
- First description ofFrontiers in cellular and infection microbiology · 2023Article
- A Perspective on the Molecular Identification, Classification, and Epidemiology of Enterocytozoon bieneusi of Animals.Experientia supplementum (2012) · 2022Article
- Enterocytozoon bieneusi Genotypes and Infections in the Horses in Korea.The Korean journal of parasitology · 2021Article
- Prevalence and genotypic identification of Cryptosporidium spp. and Enterocytozoon bieneusi in captive Asiatic black bears (Ursus thibetanus) in Heilongjiang and Fujian provinces of China.BMC veterinary research · 2020Article
- Novel genotypes and multilocus genotypes of Enterocytozoon bieneusi in two wild rat species in China: potential for zoonotic transmission.Parasitology research · 2020Article
- Multilocus Sequence Typing ofFrontiers in microbiology · 2020Article
- Prevalence and multilocus genotypes of Enterocytozoon bieneusi in alpacas (Vicugna pacos) in Shanxi Province, northern China.Parasitology research · 2019Article
- New genotypes and molecular characterization ofInternational journal for parasitology. Parasites and wildlife · 2019Article
- New genotypes and molecular characterization ofInternational journal for parasitology. Parasites and wildlife · 2019Article
- Molecular Detection and Genotyping ofFrontiers in microbiology · 2019Article
- Multilocus Sequence Typing and Population Genetic Analysis ofFrontiers in genetics · 2019Article
- Human-Pathogenic Enterocytozoon bieneusi in Captive Giant Pandas (Ailuropoda melanoleuca) in China.Scientific reports · 2018Article
- Prevalence, genotypes, and risk factors of Enterocytozoon bieneusi in Asiatic black bear (Ursus thibetanus) in Yunnan Province, Southwestern China.Parasitology research · 2018Article
- Molecular characterization and new genotypes of Enterocytozoon bieneusi in minks (Neovison vison) in China.Parasite (Paris, France) · 2018Article
- Article
- Population genetics of Enterocytozoon bieneusi in captive giant pandas of China.Parasites & vectors · 2017Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enterocytozoon bieneusi is an obligate eukaryotic intracellular parasite that infects a wide variety of vertebrate and invertebrate hosts. Although considerable research has been conducted on this organism, relatively little information is available on the occurrence of E. bieneusi in captive Asiatic black bears. The present study was performed to determine the prevalence, genetic diversity, and zoonotic potential of E. bieneusi in captive Asiatic black bears in zoos in southwestern China. Fecal specimens from Asiatic black bears in four zoos, located in four different cities, were collected and analyzed for the prevalence of E. bieneusi. The average prevalence of E. bieneusi was 27.4% (29/106), with the highest prevalence in Guiyang Zoo (36.4%, 16/44). Altogether, five genotypes of E. bieneusi were identified among the 29 E. bieneusi-positive samples, including three known genotypes (CHB1, SC02, and horse2) and two novel genotypes named ABB1 and ABB2. Multi-locus sequence typing using three microsatellites (MS1, MS3, and MS7) and one minisatellite (MS4) revealed V, III, V, and IV genotypes at these four loci, respectively. Phylogenetic analysis showed that the genotypes SC02 and ABB2 were clustered into group 1 of zoonotic potential, the genotypes CHB1 and ABB1 were clustered into a new group, and the genotype horse2 was clustered into group 6 of unclear zoonotic potential. In conclusion, this study identified two novel E. bieneusi genotypes in captive Asiatic black bears, and used microsatellite and minisatellite markers to reveal E. bieneusi genetic diversity. Moreover, our findings show that genotypes SC02 (identified in humans) and ABB2 belong to group 1 with zoonotic potential, suggesting the risk of transmission of E. bieneusi from Asiatic black bears to humans and other animals.
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