SynthesisPloS one2017
Prophylactic mesh placement for the PREvention of paraSTOmal hernias: The PRESTO systematic review and meta-analysis.
Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 7 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Umbrella review of systematic reviews on the efficacy and safety of using mesh in the prevention of parastomal hernias.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Effects of different mesh materials on complications after prophylactic placement for stoma formation: a systematic review and network meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Prophylactic mesh placement at index permanent end colostomy creation to prevent parastomal hernia-an updated meta-analysis.International journal of colorectal disease · 2021Pooled it
- Closure of stoma site with or without prophylactic mesh reinforcement: a systematic review and meta-analysis.International journal of colorectal disease · 2020Pooled it
- Italian guidelines for the surgical management of enteral stomas in adults.Techniques in coloproctology · 2019Guideline
- Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.The Cochrane database of systematic reviews · 2019Pooled it
- Prosthetic mesh placement for the prevention of parastomal herniation.The Cochrane database of systematic reviews · 2018Pooled it
- Propensity Score Analysis of the Utility of Supervised Perioperative Abdominal Wall Exercises for the Prevention of Parastomal Hernia.Nursing reports (Pavia, Italy) · 2025Article
- Prophylactic Mesh in Parastomal Hernia Prevention: Current Evidence.Journal of abdominal wall surgery : JAWS · 2025Review
- Risk factors for wound complications after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) compared to repeated liver resection - a propensity score matching analysis.Langenbeck's archives of surgery · 2024Article
- Prophylactic retromuscular mesh placement for parastomal hernia prevention: a retrospective cohort study of permanent colostomies and ileostomies.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- [Stoma-associated complications-Prevention strategy and treatment concepts].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Article
- Synthetic Mesh in Contaminated Abdominal Wall Surgery: Friend or Foe? A Literature Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Review
- [Prophylaxis of parastomal, perineal and incisional hernias in colorectal surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Robotic Sugarbaker parastomal hernia repair: technique and outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Prophylactic mesh augmentation using permanent synthetic mesh: outcomes of keyhole and Stapled Ostomy Reinforcement with Retromuscular Mesh techniques.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Incidence and risk factors of parastomal hernia after radical cystectomy and ileal conduit diversion: a systematic review and meta-analysis.Translational cancer research · 2021Article
- [Principles and parallels of prevention and repair of parastomal hernia with meshes].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- Modified keyhole technique for the treatment of parastomal hernia: A case series.International journal of surgery case reports · 2020Article
- Quality Assessment and Risk of Bias of Systematic Reviews of Prophylactic Mesh for Parastomal Hernia Prevention Using AMSTAR and ROBIS Tools.World journal of surgery · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundParastomal hernia (PH) is the most common complication after ostomy formation. Prophylactic mesh placement may be effective in reducing the rate of PH at the stoma site. The aims of this systematic review were to summarize the evidence with regard to the safety and effectiveness in comparison with the standard procedure without mesh placement and to identify important risk constellations.
methodA systematic literature search was performed in PubMed, EMBASE and the Cochrane library with no language or date restrictions. Randomized (RCTs) and non-randomized controlled trials (nRCTs) were included. The main outcomes of interest were PH (primary outcome) rate and stoma-related complications (secondary outcomes) such as stenosis or fistula. Statistical analysis included meta-analyses of pooled data and subgroup analyses.
resultsEleven trials (eight RCTs; three nRCTs) with a total of 755 patients were included. PH rate varied from 0% to 59% in the intervention and from 20% to 94% in the control group. RCTs showed a significant reduction of PH rate in the mesh group (OR 0.24; 95% CI 0.10 to 0.58, p = 0.034), whereas included nRCTs did not. No significant differences were observed in postoperative complication rates. Subgroup analyses showed superiority of non-absorbable meshes and sublay mesh positioning in open surgery.
conclusionProphylactic mesh placement is safe and reduces PH rate. A recommendation for prophylactic non-absorbable meshes in a sublay position can be made for patients undergoing open colorectal operations with end-ostomies. Further research endeavors should focus on patient-oriented outcomes, not only PH rate, with respect to tailored treatment in specific patient populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.