Evidence map›Paper›PMID 28182444›Full record

ArticleJournal of abnormal psychology2017

A network approach to modeling comorbid internalizing and alcohol use disorders.

Justin J Anker, Miriam K Forbes, Zack W Almquist, Jeremiah S Menk, Paul Thuras, Amanda S Unruh, Matt G Kushner

Open access · hybridAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

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  20. Nexus of despair: A network analysis of suicidal ideation among veterans.Archives of suicide research : official journal of the International Academy for Suicide Research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Justin J AnkerDepartment of Psychiatry.ORCID 0000-0002-2115-5170
Miriam K ForbesDepartment of Psychiatry.
Zack W AlmquistDepartment of Sociology.ORCID 0000-0002-1967-123X
Jeremiah S MenkBiostatistical Design and Analysis Center, Clinical and Translational Science Institute.
Paul ThurasMedical Center.
Amanda S UnruhDepartment of Psychiatry.
Matt G KushnerDepartment of Psychiatry.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Dismantling the Components and Dosing of CBT for Co-Occurring DisordersR01AA015069 · NIAAA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI KUSHNER, MATT G · 2005 to 2018
$3.8M
Comorbidity: Substance Use Disorders and Other Psychiatric ConditionsT32DA037183 · NIDA · UNIVERSITY OF MINNESOTA · PI Anna Zilverstand · 2014 to 2026
$3.2M
Physiological Stress Reactivity as a Determinant in Co-occurring Alcohol Use and Anxiety Disorder: Diagnosis and Alcohol Use OutcomesK01AA024805 · NIAAA · UNIVERSITY OF MINNESOTA · PI ANKER, JUSTIN JACK · 2017 to 2021
$726k
NCATS NIH HHS UL1 TR002494NIAAA NIH HHS K01 AA024805NIAAA NIH HHS R01 AA015069NIDA NIH HHS T32 DA037183
6 · The paper itself

Abstract

Internalizing disorders co-occur with alcohol use disorder (AUD) at a rate that exceeds chance and compromise conventional AUD treatment. The "vicious cycle" model of comorbidity specifies drinking to cope (DTC) as a link between these disorders that, when not directly addressed, undermines the effectiveness of conventional treatments. Interventions based on this model have proven successful but there is no direct evidence for how and to what extent DTC contributes to the maintenance of comorbidity. In the present study, we used network analysis to depict associations between syndrome-specific groupings of internalizing symptoms, alcohol craving, and drinking behavior, as well as DTC and other extradiagnostic variables specified in the vicious cycle model (e.g., perceived stress and coping self-efficacy). Network analyses of 362 individuals with comorbid anxiety and AUD assessed at the beginning of residential AUD treatment indicated that while internalizing conditions and drinking elements had only weak direct associations, they were strongly connected with DTC and perceived stress. Consistent with this, centrality indices showed that DTC ranked as the most central/important element in the network in terms of its "connectedness" to all other network elements. A series of model simulations-in which individual elements were statistically controlled for-demonstrated that DTC accounted for all the relationships between the drinking-related elements and internalizing elements in the network; no other variable had this effect. Taken together, our findings suggest that DTC may serve as a "keystone" process in maintaining comorbidity between internalizing disorders and AUD. (PsycINFO Database Record

Indexed as

Models, PsychologicalAdaptation, PsychologicalAdultAlcoholismAnxiety DisordersComorbidityData Interpretation, StatisticalFemaleHumansMale

Identifiers

PMID28182444
PMCPMC5388354
OpenAlexW2586518964

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.