Evidence map›Paper›PMID 28182154›Full record

ArticleTurkish journal of ophthalmology2017

Anterior Segment Findings in Women with Polycystic Ovary Syndrome.

Seda Karaca Adıyeke, Ibrahim Karaca, Suna Yıldırım, Mehmet Adıyeke, İbrahim Uyar, Gamze Türe

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Hormones and dry eye disease.Indian journal of ophthalmology · 2023
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Seda Karaca AdıyekeTepecik Training and Research Hospital, Ophthalmology Clinic, İzmir, Turkey.
Ibrahim KaracaAliağa State Hospital, Gynecology and Obstetrics Clinic, İzmir, Turkey.
Suna YıldırımTepecik Training and Research Hospital, Gynecology and Obstetrics Clinic, İzmir, Turkey.
Mehmet AdıyekeBergama State Hospital, Gynecology and Obstetrics Clinic, İzmir, Turkey.
İbrahim UyarTepecik Training and Research Hospital, Gynecology and Obstetrics Clinic, İzmir, Turkey.
Gamze TüreTepecik Training and Research Hospital, Ophthalmology Clinic, İzmir, Turkey.
Izmir Tepecik Eğitim ve Araştırma Hastanesi · TRSivas State Hospital · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to investigate the anterior segment in women with polycystic ovary syndrome (PCOS) and to compare them with those of healthy reproductive-age female volunteers. MATERIALS AND

methodsThe study included 50 right eyes of 50 women with PCOS (group 1) and 50 right eyes of 50 healthy women (group 2). Intraocular pressure, Schirmer's test, tear film break-up time and central corneal thickness were evaluated in all subjects. Correlations between serum hormone (estradiol and testosterone) levels and observed findings were also investigated.

resultsMean central corneal thickness values were significantly higher in the PCOS group (p=0.001). The mean intraocular pressures values were similar between the two groups (p=0.560). Schirmer's test results and tear film break-up time values were significantly lower in the PCOS group (p=0.001 and p=0.001 respectively). Serum estradiol levels were moderately positively correlated with mean central corneal thickness (r=0.552), weakly positively correlated with intraocular pressure (r=0.351) and weakly negatively correlated with tear film break-up time (r=-0.393). Serum free testosterone levels were weakly correlated with intraocular pressure (r=0.342) and central corneal thickness (r=0.303), and showed weak negative correlations with Schirmer's test results (r=-0.562) and tear film break-up time (r=-0.502).

conclusionPCOS leads to physiological and structural changes in the eye. Dry eye symptoms were more severe and central corneal thickness measurements were greater in patients with PCOS. Those are correlated serum testosterone and estradiol levels.

Indexed as

corneal thicknessDry eyePolycystic ovary syndrome

Identifiers

PMID28182154
PMCPMC5282537
OpenAlexW2574518314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.