Evidence map›Paper›PMID 28182053›Full record

ArticleDental research journal

Correlation between dental caries experience and mutans streptococci counts by microbial and molecular (polymerase chain reaction) assay using saliva as microbial risk indicator.

S G Damle, Ashish Loomba, Abhishek Dhindsa, Ashu Loomba, Vikas Beniwal

Open access · goldAbstract read
In one paragraph

Article in Dental research journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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  9. Oral Microbiome:Frontiers in microbiology · 2022
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  10. Description ofThe Saudi dental journal · 2020
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  12. Increasing salivary IgA and reducingJournal of dental sciences · 2019
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  14. DNA profiling ofDental research journal
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S G DamleDepartment of Pediatric and Preventive Dentistry, M.M. College of Dental Sciences and Research, M.M. University, Mullana, Haryana, India.
Ashish LoombaDepartment of Pediatric and Preventive Dentistry, M.M. College of Dental Sciences and Research, M.M. University, Mullana, Haryana, India.
Abhishek DhindsaDepartment of Pediatric and Preventive Dentistry, M.M. College of Dental Sciences and Research, M.M. University, Mullana, Haryana, India.
Ashu LoombaDepartment of Public Health Dentistry, Dr. Loomba's Family Dental Clinic, Mohali, Punjab, India.
Vikas BeniwalDepartment of Biotechnology, M.M. Engineering College, M.M. University, Mullana, Haryana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the relationships of quantitative salivary levels of mutans streptococci (MS) in children, aged 3-6 years and 12-15 years, exhibiting variable patterns of caries activity, and to compare the association of MS in saliva using microbial and molecular (polymerase chain reaction [PCR]) assay. MATERIALS AND

methodsIn this cross-sectional observational study, eighty children were included, forty children each in Group I (3-6 years) and Group II (12-15 years). Children were further divided into two subgroups (Group IC, INC and Group IIC, IINC) based on their dental caries status. Saliva samples were collected and plated onto Mitis Salivarius-Bacitracin agar plates. After detection of MS, DNA was isolated and purified, and MS were evaluated using the PCR and AP-PCR.

resultsOf the selected 80 children, 42 were male and 38 were female. In Group IC, the mean colony count was 2.27 ± 0.54 × 10

conclusionThe mean colony count increased with increasing age and was also more in children with dental caries. Based on the matrices generated by the PCR analysis using coefficient slipped-strand mispairing, wide range of genetic diversity was seen in cases of children with and without clinically detectable caries.

Indexed as

Dental cariespolymerase chain reactionsaliva

Identifiers

PMID28182053
PMCPMC5256021
OpenAlexW2567052240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.