Evidence map›Paper›PMID 28181997›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2017

Inter-center variation in death or tracheostomy placement in infants with severe bronchopulmonary dysplasia.

K Murthy, N F M Porta, J M Lagatta, I Zaniletti, W E Truog, T R Grover, L D Nelin, R C Savani

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Identifying predictors of tracheostomy or death in preterm infants with grade 3 BPD.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  3. Inter-center variations in length of hospitalization for infants with congenital jejunal or ileal atresia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  4. Dexmedetomidine and midazolam usage and association with BSRI scores in preterm infants with chronic respiratory failure.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  5. Development of an interdisciplinary tool to assess severe BPD phase of illness and application evaluating impact of tracheostomy.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Interdisciplinary clinical bronchopulmonary dysplasia programs: development, evolution, and maturation.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  7. Article
  8. Toward precision for bronchopulmonary dysplasia: Moving past current definitions.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  9. Review
  10. Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  11. Article
  12. The NICU tracheostomy team: multidisciplinary collaboration for improvement in survival of complex patients.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  13. In-hospital mortality and length of hospital stay in infants requiring tracheostomy with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  14. Article
  15. Transpyloric feeding is associated with adverse in-hospital outcomes in infants with severe bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. A review and guide to nutritional care of the infant with established bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

K MurthyDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University and The Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
N F M PortaDepartment of Pediatrics, Feinberg School of Medicine, Northwestern University and The Ann &Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.
J M LagattaDepartment of Pediatrics, Medical College of Wisconsin and The Children's Hospital of Wisconsin, Milwaukee, WI, USA.
I ZanilettiDepartment of Analytics, Children's Hospital Association, Inc, Overland Park, KS &Department of Statistics, University of Missouri, Columbia, MO, USA.
W E TruogDepartment of Pediatrics, University of Missouri Kansas City School of Medicine and The Center for Infant Pulmonary Disorders, Children's Mercy Hospitals &Clinics, Kansas City, MO, USA.
T R GroverDepartment of Pediatrics, University of Colorado School of Medicine and The Colorado Children's Hospital, Aurora, CO, USA.
L D NelinDepartment of Pediatrics and Center for Perinatal Research, The Ohio State University College of Medicine and The Nationwide Children's Hospital, Columbus, OH, USA.
R C SavaniDepartment of Pediatrics, University of Texas Southwestern Medical Center and the Children's Medical Center of Dallas, Dallas, TX, USA.
Children's Hospital Colorado · USChildren's Hospital of Wisconsin · USChildren's Mercy Hospital · USLurie Children's Hospital · USNationwide Children's Hospital · USNorthwestern University · USThe University of Texas Southwestern Medical Center · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the presence and sources of inter-center variation (ICV) in the risk of death or tracheostomy placement (D/T) among infants with severe bronchopulmonary dysplasia (sBPD)Study design:We analyzed the Children's Hospitals Neonatal Database between 2010 and 2013 to identify referred infants born <32 weeks' gestation with sBPD. The association between center and the primary outcome of D/T was analyzed by multivariable modeling. Hypothesized diagnoses/practices were included to determine if these explained any observed ICV in D/T.

resultsD/T occurred in 280 (20%) of 1383 eligible infants from 21 centers. ICV was significant for D/T (range 2-46% by center, P<0.001) and tracheostomy placement (n=187, range 2-37%, P<0.001), but not death (n=93, range 0-19%, P=0.08). This association persisted in multivariable analysis (adjusted center-specific odds ratios for D/T varied 5.5-fold, P=0.009).

conclusionsICV in D/T is apparent among infants with sBPD. These results highlight that the indications for tracheostomy (and subsequent chronic ventilation) remain uncertain.

Indexed as

Infant, Extremely PrematureBronchopulmonary DysplasiaDatabases, FactualFemaleGestational AgeHumansInfantInfant, NewbornIntensive Care Units, NeonatalMaleMultivariate AnalysisSeverity of Illness IndexTracheostomyUnited States

Identifiers

PMID28181997
OpenAlexW2587439584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.