Evidence map›Paper›PMID 28181542›Full record

ArticleScientific reports2017

Elongation factor P restricts Salmonella's growth by controlling translation of a Mg

Eunna Choi, Soomin Choi, Daesil Nam, Shinae Park, Yoontak Han, Jung-Shin Lee, Eun-Jin Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Translation factors that keep the ribosome Pro-active.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Review
  3. Pleiotropic roles of elongation factor P inMicrobiology spectrum · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. A Simple Assay to AssessFrontiers in microbiology · 2020
    Article
  13. Article
  14. TheFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eunna ChoiDepartment of Genetic Engineering and Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Soomin ChoiDepartment of Genetic Engineering and Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Daesil NamDivision of Microbiology, Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon 16419, South Korea.
Shinae ParkDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon 24341, South Korea.
Yoontak HanDepartment of Genetic Engineering and Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Jung-Shin LeeDepartment of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon 24341, South Korea.
Eun-Jin LeeDepartment of Genetic Engineering and Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, South Korea.
Kyung Hee University · KRKangwon National University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When a ribosome translates mRNA sequences, the ribosome often stalls at certain codons because it is hard to translate. Consecutive proline codons are such examples that induce ribosome stalling and elongation factor P (EF-P) is required for the stalled ribosome to continue translation at those consecutive proline codons. We found that EF-P is required for translation of the mgtB gene encoding a Mg

Indexed as

Gene Expression Regulation, BacterialProtein BiosynthesisAdenosine TriphosphatasesAnimalsBacterial ProteinsCation Transport ProteinsCell LineGene Expression ProfilingMacrophagesMice, Inbred C3HMicrobial ViabilityPeptide Elongation FactorsSalmonella Infections, AnimalSalmonella typhimuriumVirulenceAdenosine TriphosphatasesBacterial ProteinsCation Transport Proteinsfactor EF-PMgtB protein, Salmonella typhimuriumPeptide Elongation Factors

Identifiers

PMID28181542
PMCPMC5299641
OpenAlexW2586889022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.