Evidence map›Paper›PMID 28181491›Full record

ReviewNature communications2017

The molecular basis of endothelial cell plasticity.

Elisabetta Dejana, Karen K Hirschi, Michael Simons

Abstract readReview
In one paragraph

Review in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 276 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
276citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

276 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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216 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elisabetta DejanaVascular Biology Unit, FIRC Institute of Molecular Oncology, Milan 20129, Italy.
Karen K HirschiYale Cardiovasc. Res. Center, Departments of Internal Medicine, Genetics and Biomedical Engineering New Haven, Connecticut CT06511, USA.ORCID 0000-0001-7116-0130
Michael SimonsYale Cardiovascular Research Center, Department of Internal Medicine and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut CT06511, USA.ORCID 0000-0003-0348-7734

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Surgery / Physiology CoreP01HL107205 · NHLBI · YALE UNIVERSITY · PI SIMONS, MICHAEL · 2012 to 2022
$18.8M
Angiogensis and ischemiaR01HL053793 · NHLBI · YALE UNIVERSITY · PI SIMONS, MICHAEL · 1996 to 2017
$7.3M
Tissue Chips for Rare Disease: Adding Timothy Syndrome to the HeLIVaSkCa platformUH3EB017103 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2014 to 2016
$7.1M
Neurovascular RegenerationR01EB016629 · NIBIB · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2014 to 2018
$4.8M
Multi-tissue platform for modeling systemic pathologiesUG3EB025765 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VUNJAK-NOVAKOVIC, GORDANA · 2017 to 2019
$2.8M
Specification of Hemogenic Endothelial CellsR01HL128064 · NHLBI · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2015 to 2018
$2.6M
Integrated heart-liver-vascular systems for drug testing in human health and diseUH2EB017103 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2012 to 2013
$1.7M
Human Endothelial Cell DifferentiationR01HL096360 · NHLBI · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2009 to 2013
$1.5M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS P01 HL107205NHLBI NIH HHS R01 HL053793NHLBI NIH HHS R01 HL096360NHLBI NIH HHS R01 HL128064NIBIB NIH HHS R01 EB016629NIBIB NIH HHS UG3 EB025765NIBIB NIH HHS UH2 EB017103NIBIB NIH HHS UH3 EB017103
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell PlasticityAnimalsCell LineageEmbryonic DevelopmentEndothelial CellsHomeostasisHumansSignal Transduction

Identifiers

PMID28181491
PMCPMC5309780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.