Evidence map›Paper›PMID 28181297›Full record

ReviewEnvironmental and molecular mutagenesis2017

Induction of oxidative stress by bisphenol A and its pleiotropic effects.

Natalie R Gassman

Open access · greenAbstract readReview
In one paragraph

Review in Environmental and molecular mutagenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it, 309 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. International journal of molecular sciences · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Forever particles: histochemistry in the plasticene age.European journal of histochemistry : EJH · 2025
    Review
  18. Review
  19. Article
  20. Role ofPharmaceuticals (Basel, Switzerland) · 2025
    Article

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Natalie R GassmanUniversity of South Alabama Mitchell Cancer Institute, Mobile, Alabama, 36604-1405.
University of South Alabama · US

Funding

Bisphenol A modulation of DNA repair triggered by environmental genotoxic stressR00ES023813 · NIEHS · UNIVERSITY OF SOUTH ALABAMA · PI GASSMAN, NATALIE ROSE · 2016 to 2018
$747k
NIEHS NIH HHS R00 ES023813
6 · The paper itself

Abstract

Bisphenol A (BPA) has become a target of intense public scrutiny since concerns about its association with human diseases such as obesity, diabetes, reproductive disorders, and cancer have emerged. BPA is a highly prevalent chemical in consumer products, and human exposure is thought to be ubiquitous. Numerous studies have demonstrated its endocrine disrupting properties and attributed exposure with cytotoxic, genotoxic, and carcinogenic effects; however, the results of these studies are still highly debated and a consensus about BPA's safety and its role in human disease has not been reached. One of the contributing factors is a lack of molecular mechanisms or modes of action that explain the diverse and pleiotropic effects observed after BPA exposure. The increase in BPA research seen over the last ten years has resulted in more studies that examine molecular mechanisms and revealed links between BPA-induced oxidative stress and human disease. Here, a review of the current literature examining BPA exposure and the induction of reactive oxygen species (ROS) or oxidative stress will be provided to examine the landscape of the current BPA literature and provide a framework for understanding how induction of oxidative stress by BPA may contribute to the pleiotropic effects observed after exposure. Environ. Mol. Mutagen. 58:60-71, 2017. © 2017 Wiley Periodicals, Inc.

Indexed as

DNA DamageAnimalsAntioxidantsBenzhydryl CompoundsBisphenol A CompoundsEnvironmental PollutantsGenetic PleiotropyHumansOxidative StressPhenolsReactive Oxygen SpeciesAntioxidantsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEnvironmental PollutantsPhenolsReactive Oxygen SpeciesantioxidantDNA damageprooxidantreactive oxygen species

Identifiers

PMID28181297
PMCPMC5458620
OpenAlexW2586967350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.