ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2017
Management of Hypertension in the Elderly and Frail Elderly.
Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- The effects of exercise training on hypertensive older adults: an umbrella meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Pooled it
- Frailty and sex differences in blood pressure control in older adults.Scientific reports · 2026Article
- Observational
- Diagnostic and Therapeutic Approach to Different Hypertensive Phenotypes According to the 2023 ESH Guidelines.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Review
- Complex Patterns of Antihypertensive Treatment Changes in Long-Term Care Residents.Journal of the American Medical Directors Association · 2024Article
- Frailty and chronic diseases: A bi-directional relationship.Aging medicine (Milton (N.S.W)) · 2024Review
- Orthogeriatric Assessment of the Elderly Patient with Fragility Hip Fracture: Preliminary Results of a Prospective Study.Journal of personalized medicine · 2023Article
- TIMES TO ACT. Italian-Spanish-Polish-Uzbek Expert Forum Position Paper 2022. Dyslipidemia and arterial hypertension: The two most important and modifiable risk factors in clinical practice.Cardiology journal · 2022Article
- Non-conveyance of older adult patients and association with subsequent clinical and adverse events after initial assessment by ambulance clinicians: a cohort analysis.BMC emergency medicine · 2021Article
- Hypertension Management and Control in Italy: A Real-World Survey in Elderly Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Real-world Antihypertensive Treatment Patterns, Treatment Adherence, and Blood Pressure Control in the Elderly: An Italian Awareness-raising Campaign on Hypertension by Senior Italia FederAnziani, the Italian Society of Hypertension and the Italian Federation of General Practitioners.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Change in Prescribing for Secondary Prevention of Stroke and Coronary Heart Disease in Finnish Nursing Homes and Assisted Living Facilities.Drugs & aging · 2019Article
- Prevention and Treatment of Acute Stroke in the Nonagenarians and Beyond: Medical and Ethical Issues.Current treatment options in neurology · 2019Review
- Hypertension Management at Older Age: An Update.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019Review
- How May Coexisting Frailty Influence Adherence to Treatment in Elderly Hypertensive Patients?International journal of hypertension · 2019Article
- Executive Summary of the 2018 Joint Consensus Document on Cardiovascular Disease Prevention in Italy.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018Review
- Neuroimaging Signatures of Cerebral Small Vessel Disease at Blood Pressure Cutoff Levels of 130/80 and 140/90 mmHg: A Population-Based Study in Community-Dwellers Aged ≥ 60 Years.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018Article
- [Antihypertensive therapy in the elderly].Herz · 2018Review
- Hypertension and Frailty Syndrome in Old Age: Current Perspectives.Cardiac failure review · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An elevated systolic but not diastolic blood pressure level represents a common finding in elderly patients and is associated with an increased risk for developing coronary artery disease, cerebrovascular disease, peripheral artery disease, progressive cognitive decline and renal failure. Although less frequently, elderly patients manifest not only with systolic but also diastolic hypertension. Also in this case, the elderly patient will present an increased risk for developing hypertension-related abnormalities. Based on several trials conducted in patients ≥65 years and one single trial in patients ≥80 years the most recent European guidelines recommend antihypertensive treatment in elderly hypertensive patients with a systolic blood pressure ≥60 mmHg, with a systolic target between 140 and 150 mmHg. In fit elderly patients <80 years treatment may be considered at a systolic level ≥140 mmHg with a target SBP <140 mmHg if treatment is well tolerated. Despite of the above, at least three issues related to antihypertensive drug treatment in aged individuals are still debated, particularly after the publication of a recent large scale clinical trial that included also 2.636 patients ≥75 years and a study in nursing home residents ≥80 years, i.e. the frailest oldest patients: (1) the blood pressure threshold at which antihypertensive drug should be initiated, (2) the blood pressure targets of the therapeutic intervention, and (3) the approach to frail elderly hypertensive patients. This review will critically review the evidence available so far on these important issues as well as the position of current guidelines and consensus statements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.