Evidence map›Paper›PMID 28181150›Full record

SynthesisJournal of nephrology2018

Effectiveness of targeted screening for chronic kidney disease in the community setting: a systematic review.

Pankti A Gheewala, Syed Tabish R Zaidi, Matthew D Jose, Luke Bereznicki, Gregory M Peterson, Ronald L Castelino

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pankti A GheewalaDivision of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Private Bag 26, Hobart, TAS, 7001, Australia. Pankti.Gheewala@utas.edu.au.
Syed Tabish R ZaidiDivision of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Private Bag 26, Hobart, TAS, 7001, Australia.
Matthew D JoseSchool of Medicine, Faculty of Health, University of Tasmania, Hobart, TAS, 7000, Australia.
Luke BereznickiDivision of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Private Bag 26, Hobart, TAS, 7001, Australia.
Gregory M PetersonDivision of Pharmacy, School of Medicine, Faculty of Health, University of Tasmania, Private Bag 26, Hobart, TAS, 7001, Australia.
Ronald L CastelinoSydney Nursing School, The University of Sydney, Sydney, NSW, 2050, Australia.
University of Tasmania · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTargeted screening interventions for chronic kidney disease (CKD) are increasingly being implemented in various community settings. However, the overall success of these programs is uncertain. Therefore, the aim of this review is to determine whether targeted screening is effective in detecting people with undiagnosed CKD.

methodsWe performed a systematic literature review, and included studies of targeted screening intervention implemented in any community-based setting. Studies were required to have targeted people aged ≥18 years, and multiple CKD risk factors from the following: diabetes, hypertension, cardiovascular disease and family history of kidney disease. The outcome measures were percentages of participants with positive screening test results and diagnosed with CKD at follow-up.

resultsNine studies met the inclusion criteria. Eight studies reported the percentage of participants with positive screening test results, which ranged from 7 to 60.3%. Only two studies repeated the diagnostic tests to detect CKD, and confirmed the chronicity of CKD in 20.5 and 17.1% of screened participants. The most commonly used screening tests were albumin creatinine ratio (≥3.4 mg/mmol), and estimated glomerular filtration rate (eGFR) (<60 ml/min/1.73 m

conclusionsThis systematic review found significant variation in the methods that were used to detect CKD, with the majority of studies reporting results based on only single albuminuria or eGFR values. Future targeted screening programs should appropriately use the 2012 KDIGO guidelines in order to detect CKD, which is necessary to determine the benefit of these programs when implemented in community-settings.

Indexed as

Community Health ServicesGlomerular Filtration RateAdultAgedAlbuminuriaEarly DiagnosisFemaleHumansKidneyMaleMass ScreeningMiddle AgedPredictive Value of TestsPrognosisRenal Insufficiency, ChronicRisk FactorsChronic kidney diseaseCommunity settingEarly detectionEffectivenessSystematic reviewTargeted screening

Identifiers

PMID28181150
OpenAlexW2587440306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.