Evidence map›Paper›PMID 28179624›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2017

Analysis of beat-to-beat blood pressure variability response to the cold pressor test in the offspring of hypertensive and normotensive parents.

Dan Wu, Lin Xu, Derek Abbott, William Kongto Hau, Lijie Ren, Heye Zhang, Kelvin K L Wong

Abstract read
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In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. The connection between hypertension and diabetes and their role in heart and kidney disease development.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Dan WuShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Lin XuDepartment of Cardiology, Guangzhou General Hospital of Guangzhou Military Region, PLA, Guangzhou, China.
Derek AbbottCentre for Biomedical Engineering and School of Electrical and Electronic Engineering, University of Adelaide, Adelaide, SA, Australia.
William Kongto HauInstitute of Cardiovascular Medicine and Research, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Lijie RenDepartment of Neurology, Shenzhen Second People's Hospital, Shenzhen, China.
Heye ZhangShenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Kelvin K L WongSchool of Medicine, Western Sydney University, Sydney, NSW, Australia.
Shenzhen Institutes of Advanced Technology · CNGeneral Hospital of Guangzhou Military Command · CNShenzhen Second People's Hospital · CNUniversity of Adelaide · AUUniversity of Hong Kong · HKWestern Sydney University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal autonomic nervous regulation has an important role in the development of hypertension. As to whether blood pressure (BP) or BP variability represents the proper characteristics for predisposition to hypertension in Chinese young adults remains controversial. We studied the properties of the indices extracted from beat-to-beat BP during a 13 min cold pressor test (CPT). In this study, 69 Chinese young adults including 34 offspring of hypertensive parents (OHPs; 25.6±2.5 years) and 35 offspring of normotensive parents (ONPs; 25.3±2.3 years) were analyzed. We assessed the differences between the two groups regarding mean beat-to-beat BP and variability indices. Beat-to-beat BP variability indices included time-domain indices and frequency-domain indices. Our results showed that the differences in beat-to-beat systolic BP and mean BP levels between the OHPs and the ONPs were statistically significant (P<0.05). Furthermore, more BP variability indices in the frequency domain were significantly different between the two groups. We concluded that BP variability was superior to BP as an index to evaluate the cardiovascular and sympathetic reactivity to the CPT. Moreover, compared with time-domain BP variability, we found more differences in frequency-domain BP variability between the two groups, thus indicating that frequency-domain BP variability may be a potential index of predisposition to hypertension.

Indexed as

Blood PressureAdultCold TemperatureHeart RateHumansHypertensionYoung Adult

Identifiers

PMID28179624
OpenAlexW2586246322

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.