Evidence map›Paper›PMID 28179499›Full record

ArticleOpen biology2017

Structural, mechanistic and functional insight into gliotoxin

Stephen K Dolan, Tobias Bock, Vanessa Hering, Rebecca A Owens, Gary W Jones, Wulf Blankenfeldt, Sean Doyle

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Biofilm Formation inMicroorganisms · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Chemical Genetics inACS chemical biology · 2024
    Article
  7. Article
  8. Bioenzymatic detoxification of mycotoxins.Frontiers in microbiology · 2024
    Review
  9. Article
  10. Transcriptional profiling of a fungal granuloma reveals a low metabolic activity ofFrontiers in cellular and infection microbiology · 2023
    Article
  11. Review
  12. Article
  13. A SingleInternational journal of molecular sciences · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. At the metal-metabolite interface inMicrobiology (Reading, England) · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Stephen K DolanDepartment of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.
Tobias BockHelmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstraße 7, 38124 Braunschweig, Germany.
Vanessa HeringHelmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstraße 7, 38124 Braunschweig, Germany.
Rebecca A OwensDepartment of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.
Gary W JonesDepartment of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.
Wulf BlankenfeldtHelmholtz Centre for Infection Research, Structure and Function of Proteins, Inhoffenstraße 7, 38124 Braunschweig, Germany wulf.blankenfeldt@helmholtz-hzi.de.ORCID 0000-0001-9886-9668
Sean DoyleDepartment of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland sean.doyle@nuim.ie.ORCID 0000-0003-1679-3247
National University of Ireland, Maynooth · IEHelmholtz Centre for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gliotoxin is an epipolythiodioxopiperazine (ETP) class toxin, contains a disulfide bridge that mediates its toxic effects via redox cycling and is produced by the opportunistic fungal pathogen

Indexed as

Aspergillus fumigatusCrystallography, X-RayFungal ProteinsGliotoxinMetabolomicsMethyltransferasesModels, MolecularMutationOxidoreductasesProtein BindingProtein ConformationProteomicsS-AdenosylhomocysteineS-AdenosylmethionineToluenedithiolFungal ProteinsGliotoxinGliT protein, Aspergillus fumigatusMethyltransferasesOxidoreductasesS-AdenosylhomocysteineS-AdenosylmethionineTolueneAspergillusmethyltransferaseNRPSquantitative proteomics

Identifiers

PMID28179499
PMCPMC5356443
OpenAlexW2586677940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.