Evidence map›Paper›PMID 28179487›Full record

ArticleThe Journal of nutrition2017

Supplemental Citrulline Is More Efficient Than Arginine in Increasing Systemic Arginine Availability in Mice.

Umang Agarwal, Inka C Didelija, Yang Yuan, Xiaoying Wang, Juan C Marini

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04092439 (The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function and Blood Flow During Hyperglycemia), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04092439 nacompletednot on this mapstarted 2019, after this paper: background citation

The Effects of Watermelon Juice Supplementation on Postprandial Vascular Endothelial Function and Blood Flow During Hyperglycemia: A Pilot Study

TypeinterventionalSponsorPennington Biomedical Research CenterRan2019 to 2020Enrolled18ConditionsEndothelial DysfunctionArmsWatermelon Juice
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The roles of arginases and arginine in immunity.Nature reviews. Immunology · 2025
    Review
  16. Review
  17. L-Citrulline in Neonates: From Bench to Bed Side.Children (Basel, Switzerland) · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Umang AgarwalUSDA/Agricultural Research Service Children's Nutrition Research Center; and.
Inka C DidelijaUSDA/Agricultural Research Service Children's Nutrition Research Center; and.
Yang YuanUSDA/Agricultural Research Service Children's Nutrition Research Center; and.
Xiaoying WangUSDA/Agricultural Research Service Children's Nutrition Research Center; and.
Juan C MariniUSDA/Agricultural Research Service Children's Nutrition Research Center; and marini@bcm.edu.
Agricultural Research Service · US

Funding

Therapeutic and Metabolic Responses of Citrulline vs. Arginine SupplementationR01GM108940 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BURRIN, DOUGLAS G · 2014 to 2023
$2.2M
NIGMS NIH HHS R01 GM108940
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Animal FeedAnimalsArginaseArginineBiological AvailabilityCarrier ProteinsCitrullineDietDietary SupplementsGene Expression RegulationLiverMaleMiceMice, Inbred C57BLArginaseArginineCarrier ProteinsCitrullineamino acidargininecitrullinefirst-pass metabolismrequirements

Identifiers

PMID28179487
PMCPMC5368575
OpenAlexW2587697776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.