Evidence map›Paper›PMID 28179478›Full record

ArticleJournal of neurophysiology2017

Magnetic resonance spectroscopy of current hand amputees reveals evidence for neuronal-level changes in former sensorimotor cortex.

Carmen M Cirstea, In-Young Choi, Phil Lee, Huiling Peng, Christina L Kaufman, Scott H Frey

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Carmen M CirsteaDepartment of Physical Medicine and Rehabilitation, University of Missouri, Columbia, Missouri; cirsteac@health.missouri.edu.
In-Young ChoiDepartment of Neurology, Kansas University Medical Center, Kansas City, Kansas.
Phil LeeDepartment of Molecular and Integrative Physiology, Kansas University Medical Center, Kansas City, Kansas.
Huiling PengDepartment of Psychological Sciences, University of Missouri, Columbia, Missouri.
Christina L KaufmanChristine M. Kleinert Institute, Louisville, Kentucky.
Scott H FreyDepartment of Psychological Sciences, University of Missouri, Columbia, Missouri.
University Medical Center · USUniversity of Missouri · USChristine M. Kleinert Institute · USUniversity of Kansas Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deafferentation is accompanied by large-scale functional reorganization of maps in the primary sensory and motor areas of the hemisphere contralateral to injury. Animal models of deafferentation suggest a variety of cellular-level changes including depression of neuronal metabolism and even neuronal death. Whether similar neuronal changes contribute to patterns of reorganization within the contralateral sensorimotor cortex of chronic human amputees is uncertain. We used functional MRI-guided proton magnetic resonance spectroscopy to test the hypothesis that unilateral deafferentation is associated with lower levels of

Indexed as

AdultAgedAmputation StumpsAmputeesAspartic AcidFemaleFunctional LateralityHandHumansImaging, Three-DimensionalMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedPain MeasurementPhantom LimbAspartic AcidN-acetylaspartateallogeneic hand transplantation and hand replantationfunctional MRI-guided 1H-MR spectroscopyN-acetylaspartatesensorimotor hand territoryunilateral hand amputees

Identifiers

PMID28179478
PMCPMC5390283
OpenAlexW2587630923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.