Evidence map›Paper›PMID 28179424›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Altered methylation of specific DNA loci in the liver of

Daniel S Lupu, Luz D Orozco, Ying Wang, John M Cullen, Matteo Pellegrini, Steven H Zeisel

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. MicroRNA-129-5p is regulated by choline availability and controls EGF receptor synthesis and neurogenesis in the cerebral cortex.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  13. Dietary Modulation of the Epigenome.Physiological reviews · 2018
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Daniel S LupuDepartment of Nutrition, Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, North Carolina, USA.
Luz D OrozcoDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.
Ying WangDepartment of Clinical Nutrition, School of Medicine, Xin Hua Hospital, Shanghai Jiao Tong University, Shanghai, China.
John M CullenNorth Carolina State University, College of Veterinary Medicine, Raleigh, North Carolina, USA.
Matteo PellegriniDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.
Steven H ZeiselDepartment of Nutrition, Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, North Carolina, USA; steven_zeisel@unc.edu.
University of California, Los Angeles · USDavid H. Murdock Research Institute · USNorth Carolina State University · USShanghai Jiao Tong University · CNUniversity of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
NIDDK NIH HHS P30 DK056350NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Folate B

Indexed as

DNA MethylationAnimalsBetaine-Homocysteine S-MethyltransferaseDNAFolic AcidGlutathione TransferaseLiverMice, Inbred C57BLMice, KnockoutPrecancerous Conditionsras GTPase-Activating ProteinsReceptors, ThrombinBetaine-Homocysteine S-MethyltransferaseBhmt protein, mouseDNAFolic AcidGlutathione TransferaseIqgap2 protein, mouseprotease-activated receptor 3ras GTPase-Activating ProteinsReceptors, Thrombinbetaineepigeneticsfolatemethylome

Identifiers

PMID28179424
PMCPMC5388550
OpenAlexW2586309203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.