ArticleJournal of clinical microbiology2017
Diagnostic Accuracy of Cerebrospinal Fluid Procalcitonin in Bacterial Meningitis Patients with Empiric Antibiotic Pretreatment.
Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Diagnostic Accuracy of Cerebrospinal Fluid Presepsin vs. Procalcitonin in Post-Neurosurgical Bacterial Ventriculitis/Meningitis: A Machine Learning Analytical Approach.Journal of molecular neuroscience : MN · 2026Article
- Cerebrospinal fluid procalcitonin and neutrophil percentage: a combined biomarker for differentiating bacterial from tuberculous meningitis in antibiotic-pretreated patients.Frontiers in cellular and infection microbiology · 2026Article
- Diagnostic Test Accuracy of Serum and Cerebrospinal Fluid C-Reactive Protein in Bacterial Meningitis: A Systematic Review and Meta-Analysis.Infection & chemotherapy · 2025Article
- Procalcitonin contributes to hippocampal neuronal damage and impairment of LTP: implications for cognitive dysfunction in LPS-induced neuroinflammation rat model.Archives of microbiology · 2025Article
- The Diagnostic Utility of Cerebrospinal Fluid Procalcitonin for Acute Bacterial Meningitis and Ventriculitis in Children: A Multicenter Prospective Study.Acta medica Philippina · 2025Article
- Diagnostic accuracy of inflammatory markers in adults with suspected central nervous system infections.The Journal of infection · 2024Article
- Article
- Quantitative proteomic analysis of cerebrospinal fluid reveals CD163, A2M and full-length APP as potential diagnostic biomarkers of paediatric bacterial meningitis.Proteome science · 2022Article
- Accuracy of heparin-binding protein for the diagnosis of nosocomial meningitis and ventriculitis.Critical care (London, England) · 2022Observational
- Post-neurosurgical meningitis; gram negative bacilli vs. gram positive cocci.Caspian journal of internal medicine · 2022Article
- Restricted Diffusion Abnormalities on Magnetic Resonance Imaging in a Patient with Tuberculous Pachymeningitis.Journal of clinical neurology (Seoul, Korea) · 2021Article
- Value of lipocalin 2 as a potential biomarker for bacterial meningitis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Article
- Cerebrospinal fluid procalcitonin predicts Gram-negative bacterial meningitis in patients with empiric antibiotic pretreatment.Critical care (London, England) · 2019Article
- The Role of Procalcitonin in the Diagnosis of Meningitis: A Literature Review.Journal of clinical medicine · 2018Review
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate diagnosis of bacterial meningitis (BM) relies on cerebrospinal fluid (CSF) Gram staining and bacterial culture, which often present high false-negative rates because of antibiotic abuse. Thus, a novel and reliable diagnostic biomarker is required. Procalcitonin (PCT) has been well demonstrated to be specifically produced from peripheral tissues by bacterial infection, which makes it a potential diagnostic biomarker candidate. Here, we performed a prospective clinical study comprising a total of 143 patients to investigate the diagnostic value of CSF PCT, serum PCT, and other conventional biomarkers for BM. Patients were assigned to the BM (
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