ArticleAmerican journal of physiology. Cell physiology2017
Identification of a mammalian silicon transporter.
Article in American journal of physiology. Cell physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 54 citations in OpenAlex.
- The silicon efflux transporter BEC1 is essential for bloom formation and stress tolerance in cucumber.Journal of integrative plant biology · 2025Article
- Silicon in prevention of atherosclerosis and other age-related diseases.Frontiers in cardiovascular medicine · 2024Review
- Microporous Hydroxyapatite-Based Ceramics Alter the Physiology of Endothelial Cells through Physical and Chemical Cues.Journal of functional biomaterials · 2023Article
- Evaluating the Effectiveness of Calcium Silicate in Enhancing Soybean Growth and Yield.Plants (Basel, Switzerland) · 2023Article
- Characterization of the molecular mechanisms of silicon uptake in coccolithophores.Environmental microbiology · 2023Article
- Genome-Wide Identification of Aquaporin Genes in Adzuki Bean (International journal of molecular sciences · 2022Article
- Multidimensional Role of Silicon to Activate Resilient Plant Growth and to Mitigate Abiotic Stress.Frontiers in plant science · 2022Review
- Ionomic Approaches for Discovery of Novel Stress-Resilient Genes in Plants.International journal of molecular sciences · 2021Review
- Lsi2: A black box in plant silicon transport.Plant and soil · 2021Review
- Cooperation between passive and active silicon transporters clarifies the ecophysiology and evolution of biosilicification in sponges.Science advances · 2020Article
- Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells.Scientific reports · 2020Article
- On the Potential of Silicon as a Building Block for Life.Life (Basel, Switzerland) · 2020Article
- Physiological silicon incorporation into bone mineral requires orthosilicic acid metabolism to SiOJournal of the Royal Society, Interface · 2020Article
- Article
- Effects of Silicon Compounds on Biomineralization, Osteogenesis, and Hard Tissue Formation.Pharmaceutics · 2019Review
- Novel deletion ofJournal of genetics · 2018Article
Corrections and comments
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Authors and funding
16 authors at 9 institutions in 4 countries.
Funding
Abstract
Silicon (Si) has long been known to play a major physiological and structural role in certain organisms, including diatoms, sponges, and many higher plants, leading to the recent identification of multiple proteins responsible for Si transport in a range of algal and plant species. In mammals, despite several convincing studies suggesting that silicon is an important factor in bone development and connective tissue health, there is a critical lack of understanding about the biochemical pathways that enable Si homeostasis. Here we report the identification of a mammalian efflux Si transporter, namely Slc34a2 (also termed NaPiIIb), a known sodium-phosphate cotransporter, which was upregulated in rat kidney following chronic dietary Si deprivation. Normal rat renal epithelium demonstrated punctate expression of Slc34a2, and when the protein was heterologously expressed in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.