Evidence map›Paper›PMID 28179029›Full record

ArticleBMC research notes2017

Severe Chikungunya infection in Northern Mozambique: a case report.

Mussa Manuel Aly, Sadia Ali, Argentina Felisbela Muianga, Vanessa Monteiro, Jorge Galano Gallego, Jacqueline Weyer, Kerstin I Falk, Janusz Tadeusz Paweska, Julie Cliff, Eduardo Samo Gudo

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Mussa Manuel AlyPemba Operational Research Unit, Ministry of Health, Pemba, Mozambique.
Sadia AliNational Institute of Health, Ministry of Health, Av Eduardo Mondlane 1008, Ministry of Health Main Building, 2nd Floor, PO Box 264, Maputo, Mozambique.
Argentina Felisbela MuiangaNational Institute of Health, Ministry of Health, Av Eduardo Mondlane 1008, Ministry of Health Main Building, 2nd Floor, PO Box 264, Maputo, Mozambique.
Vanessa MonteiroNational Institute of Health, Ministry of Health, Av Eduardo Mondlane 1008, Ministry of Health Main Building, 2nd Floor, PO Box 264, Maputo, Mozambique.
Jorge Galano GallegoCabo Delgado Provincial Health Directorate, Pemba, Mozambique.
Jacqueline WeyerCentre for Emerging and Zoonotic Diseases, National Institute for Communicable Disease, National Health Laboratory Service, Sandringham, South Africa.
Kerstin I FalkThe Public Health Agency of Sweden, Stockholm, Sweden.
Janusz Tadeusz PaweskaCentre for Emerging and Zoonotic Diseases, National Institute for Communicable Disease, National Health Laboratory Service, Sandringham, South Africa.
Julie CliffCommunity Health Department, Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique.
Eduardo Samo GudoNational Institute of Health, Ministry of Health, Av Eduardo Mondlane 1008, Ministry of Health Main Building, 2nd Floor, PO Box 264, Maputo, Mozambique. esamogudojr@gmail.com.
Ministry of Health · MZNational Health Laboratory Service · ZAEduardo Mondlane University · MZKarolinska Institutet · SENational Directorate of Geology · MZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough Chikungunya virus has rapidly expanded to several countries in sub-Saharan Africa, little attention has been paid to its control and management. Until recently, Chikungunya has been regarded as a benign and self-limiting disease. In this report we describe the first case of severe Chikungunya disease in an adult patient in Pemba, Mozambique. CASE PRESENTATION: A previously healthy 40 year old male of Makonde ethnicity with no known past medical history and resident in Pemba for the past 11 years presented with a severe febrile illness. Despite administration of broad spectrum intravenous antibiotics the patient rapidly deteriorated and became comatose while developing anaemia, thrombocytopenia and later, melaena. Laboratory testing revealed IgM antibodies against Chikungunya virus. Malaria tests were consistently negative.

conclusionsThis report suggests that Chikungunya might cause unsuspected severe disease in febrile patients in Mozambique and provides insights for the improvement of national protocols for management of febrile patients in Mozambique. We recommend that clinicians should consider Chikungunya in the differential diagnosis of febrile illness in locations where Aedes aegypti mosquitos are abundant.

Indexed as

AdultAnimalsAnti-Bacterial AgentsAntibodies, ViralBlood Cell CountChikungunya FeverChikungunya virusDiagnosis, DifferentialFeverHumansImmunoglobulin MIndian Ocean IslandsLeukocytosisMaleMelenaMozambiqueAnti-Bacterial AgentsAntibodies, ViralImmunoglobulin MArbovirusesCase reportsChikungunyaFeverMozambique

Identifiers

PMID28179029
PMCPMC5299683
OpenAlexW2586703094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.