ArticleVirology journal2017
Characterization and complete genome of the virulent Myoviridae phage JD007 active against a variety of Staphylococcus aureus isolates from different hospitals in Shanghai, China.
Article in Virology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- Phenotypic and Genotypic Characterization of Novel Polyvalent Bacteriophages With PotentFrontiers in cellular and infection microbiology · 2021Trial
- A Novel Enterococcus Phage Exhibits Potent Anti-biofilm Activity Against Multidrug Resistant Strains and Protects Mice from Peritonitis Sepsis.Probiotics and antimicrobial proteins · 2026Article
- Bacteriophages and Endolysins Used in the Biocontrol ofMicroorganisms · 2025Review
- Isolation and characterization of methicillin-resistantFrontiers in microbiology · 2025Article
- Multiomics analysis of Staphylococcus aureus ST239 strains resistant to virulent Herelleviridae phages.Scientific reports · 2024Article
- Phage-Based Biosensing for Rapid and Specific Detection ofMicroorganisms · 2023Article
- Bacteriophages for the Targeted Control of Foodborne Pathogens.Foods (Basel, Switzerland) · 2023Review
- Characterization of the novel temperate Staphylococcus haemolyticus phage IME1365_01.Archives of virology · 2023Article
- Statistical optimization of a podoviral anti-MRSA phage CCASU-L10 generated from an under sampled repository: Chicken rinse.Frontiers in cellular and infection microbiology · 2023Article
- Genome Sequence of a Lytic Staphylococcus aureus Bacteriophage Isolated from Breast Milk.Microbiology resource announcements · 2022Article
- Isolation, characterization, and antibacterial activity of lytic bacteriophage against methicillin-resistantIranian journal of microbiology · 2022Article
- TSP, a virulent Podovirus, can control the growth of Staphylococcus aureus for 12 h.Scientific reports · 2022Article
- Article
- Isolation and characterization of novelFrontiers in microbiology · 2022Article
- Survival Comes at a Cost: A Coevolution of Phage and Its Host Leads to Phage Resistance and Antibiotic Sensitivity ofFrontiers in microbiology · 2021Article
- JD419, aFrontiers in microbiology · 2021Article
- Article
- Identification and Characterization of New Bacteriophages to Control Multidrug-ResistantFrontiers in microbiology · 2020Article
- Exploring the whole standard operating procedure for phage therapy in clinical practice.Journal of translational medicine · 2019Review
- Characterization of the Three New Kayviruses and Their Lytic Activity Against Multidrug-ResistantMicroorganisms · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe implementation of phage therapy is re-emerging with the increase in widespread antibiotic-resistant bacteria.
methodsStaphylococcus phage JD007 was characterized and its complete genome sequence analysed.
resultsStaphylococcus phage JD007 was classified as belonging to the Myoviridae family based on its morphology, as observed by transmission electron microscopy. Its lytic activity was stable between pH 5-11 and below 42 °C; moreover, an absorbance curve showed that nearly 90% of the viral particles had adsorbed to its host after a 20 min co-incubation. The complete genome size is 141,836 bp, making JD007 one of the largest Staphylococcus phages of Myoviridae. No identifiable resistance or virulence genes were found in the JD007 genome. JD007 was able to lyse 95% of S. aureus isolates, including the prevalent ST239-MRSA and ST59-MRSA strains isolated from different hospitals in Shanghai, China, and inhibition assays showed that JD007 could inhibit S. aureus growth at a multiplicity of infection of 0.1.
conclusionsThe results suggested that Staphylococcus phage JD007 can potentially be used in phage therapy or for the detection of S. aureus.
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