Evidence map›Paper›PMID 28179001›Full record

ArticleLipids in health and disease2017

Caryocar brasiliense oil improves cardiac function by increasing Serca2a/PLB ratio despite no significant changes in cardiovascular risk factors in rats.

Lidiane Guedes Oliveira, Lauane Gomes Moreno, Dirceu Sousa Melo, Liliane Vanessa Costa-Pereira, Mayara Medeiros de Freitas Carvalho, Paulo Henrique Evangelista Silva, Ana Maria Alves, Flávio de Castro Magalhães, Marco Fabrício Dias-Peixoto, Elizabethe Adriana Esteves

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lipids in health and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 17 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lidiane Guedes OliveiraPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Lauane Gomes MorenoPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Dirceu Sousa MeloPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Liliane Vanessa Costa-PereiraPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Mayara Medeiros de Freitas CarvalhoPrograma de Pós-Graduação em Ciências Biológicas, Universidade Federal de Ouro Preto - Campus Universitário, Morro do Cruzeiro, Ouro Preto, MG, Brazil, CEP: 35400-000.
Paulo Henrique Evangelista SilvaPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Ana Maria AlvesPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Flávio de Castro MagalhãesPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Marco Fabrício Dias-PeixotoPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000.
Elizabethe Adriana EstevesPrograma Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia (SBFis) - Universidade Federal dos Vales do Jequitinhonha e Mucuri - UFVJM, Rodovia MGT 367 - Km 583, n° 5000, Alto da Jacuba, Diamantina, MG, Brazil, CEP: 39100-000. eaesteves@yahoo.com.br.
Universidade Federal dos Vales do Jequitinhonha e Mucuri · BRUniversidade Federal de Ouro Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaryocar brasiliense (pequi) oil is high in monounsaturated fat acids (MUFA), especially oleic, and in carotenoids, which have been associated with protection against cardiovascular disease. However, this food is poorly studied in this context, especially in the cardiac function. Therefore, we investigated the effects of a long-term intake of pequi oil in systemic cardiovascular risk factors and in the ex vivo cardiac function of rats.

methodsPreviously, we determined fatty acids and carotenoids in pequi oil. Next, male rats were divided in C - control group feed a standard diet, and PO - pequi oil group fed the same diet added pequi oil (+2.25 g.100 g

resultsIn agreement with scientific data, pequi oil had expressive amounts MUFA, especially oleic acid, and carotenoids. Hepatic triglycerides (TG) were reduced by pequi oil intake (p < 0.05). All others cardiovascular risk factors were not changed. The intrinsic heart rate was lower in PO group (p < 0.05). SERCA2a content was higher in this group (p < 0.05), without affecting PLB. Also, SERCA2a/PLB ratio increased in PO group (p < 0.05).

conclusionPequi oil intake improved cardiac function ex vivo, despite no significant changes in systemic cardiovascular risk factors. The higher lipid offer in pequi oil diet, its composition in oleic acid and carotenoids could be related to those effects.

Indexed as

AnimalsBlood GlucoseBlood PressureCalcium-Binding ProteinsCarotenoidsDietary Fats, UnsaturatedEricalesFatty Acids, MonounsaturatedFruitGene ExpressionHeartHeart RateLiverMaleOleic AcidOrgan Culture TechniquesBlood GlucoseCalcium-Binding ProteinsCarotenoidsDietary Fats, UnsaturatedFatty Acids, MonounsaturatedOleic AcidPhospholambanPlant OilsSarcoplasmic Reticulum Calcium-Transporting ATPasesCardiac functionCardiovascular diseaseCarotenoidsCaryocar brasilienseMonounsaturated fatty acidsOleic acid

Identifiers

PMID28179001
PMCPMC5299795
OpenAlexW2586220865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.