SynthesisJournal of orthopaedic surgery and research2017
The correlation between the high-intensity zone on a T2-weighted MRI and positive outcomes of discography: a meta-analysis.
Synthesis in Journal of orthopaedic surgery and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The correlation between the lumbar disc MRI high-intensity zone and discogenic low back pain: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Multi-parametric quantitative MRI for characterizing of lumbar intervertebral disc high-intensity zones in patients with chronic low back pain.Journal of orthopaedic surgery and research · 2026Article
- 14. Discogenic Low Back Pain.Pain practice : the official journal of World Institute of Pain · 2025Review
- Pitfalls in the Diagnosis and Treatment of Low Back Pain in an Elite Para-athlete Successfully Treated by Transforaminal Full-endoscopic Discectomy with Thermal Annuloplasty: A Case Reports.NMC case report journal · 2025Article
- Enhancing Annular Fissures and High-Intensity Zones: Pain, Internal Derangement, and Anesthetic Response at Provocation Lumbar Discography.AJNR. American journal of neuroradiology · 2023Article
- High-Intensity Zones on MRI of the Cervical Spine in Patients: Epidemiology and Association With Pain and Disability.Global spine journal · 2022Article
- Imaging Evaluation of Intervertebral Disc Degeneration and Painful Discs-Advances and Challenges in Quantitative MRI.Diagnostics (Basel, Switzerland) · 2022Review
- The Role of Diagnostic Injections in Spinal Disorders: A Narrative Review.Diagnostics (Basel, Switzerland) · 2021Review
- Predictors of discogenic pain in magnetic resonance imaging: a retrospective study of provocative discography performed by posterolateral approach.The Korean journal of pain · 2021Article
- Intradiscal quantitative chemical exchange saturation transfer MRI signal correlates with discogenic pain in human patients.Scientific reports · 2021Observational
- Factors Predicting the Clinical Outcome After Trans-sacral Epiduroscopic Laser Decompression for Lumbar Disc Herniation.Neurospine · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis meta-analysis aimed to assess the correlation between the high-intensity zone (HIZ) of a lumbar MRI and discography.
methodsWe conducted an electronic search of the PubMed, MEDLINE, Embase, and ScienceDirect databases from their respective inceptions to October 2016 using the following search terms: "low back pain," "discogenic low back pain," "HIZ or high-intensity zone," and "discography". Relevant journals and conference proceedings were manually searched. Two reviewers independently assessed the quality of the studies, extracted data from the included studies, and analyzed the data.
resultsEleven studies were included. The results of the meta-analysis indicated that outstanding relativity and statistically significant correlations were observed between the HIZ and abnormal disc morphology (OR = 47.79; 95% CI: 17.07 to 133.77; P < 0.00001), HIZ and pain reproduction (OR = 8.65, 95% CI: 6.01 to 15.23, P < 0.00001), and HIZ and abnormal morphology pain reproduction (OR = 11.74, 95% CI: 1.99 to 69.36, P = 0.007).
conclusionsThe presence of an HIZ on a lumbar MRI T2-weighted image indicates abnormal disc morphology. There is a strong relationship between the HIZ and pain reproduction. The HIZ can be an effective index for prediction of discogenic low back pain.
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