Evidence map›Paper›PMID 28178973›Full record

ArticleBMC public health2017

Mortality from tetanus between 1990 and 2015: findings from the global burden of disease study 2015.

Hmwe H Kyu, John Everett Mumford, Jeffrey D Stanaway, Ryan M Barber, Jamie R Hancock, Theo Vos, Christopher J L Murray, Mohsen Naghavi

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 163 citations in OpenAlex.

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  16. Tetanus: recognition and management.The Lancet. Infectious diseases · 2025
    Review
  17. Article
  18. Article
  19. An Assessment of the Presence ofThe western journal of emergency medicine · 2024
    Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hmwe H KyuInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA. hmwekyu@uw.edu.ORCID 0000-0002-0449-5691
John Everett MumfordInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Jeffrey D StanawayInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Ryan M BarberInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Jamie R HancockInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Theo VosInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Christopher J L MurrayInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
Mohsen NaghaviInstitute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave. Suite 600, Seattle, WA, 98121, USA.
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough preventable, tetanus still claims tens of thousands of deaths each year. The patterns and distribution of mortality from tetanus have not been well characterized. We identified the global, regional, and national levels and trends of mortality from neonatal and non-neonatal tetanus based on the results from the Global Burden of Disease Study 2015.

methodsData from vital registration, verbal autopsy studies and mortality surveillance data covering 12,534 site-years from 1980 to 2014 were used. Mortality from tetanus was estimated using the Cause of Death Ensemble modeling strategy.

resultsThere were 56,743 (95% uncertainty interval (UI): 48,199 to 80,042) deaths due to tetanus in 2015; 19,937 (UI: 17,021 to 23,467) deaths occurred in neonates; and 36,806 (UI: 29,452 to 61,481) deaths occurred in older children and adults. Of the 19,937 neonatal tetanus deaths, 45% of deaths occurred in South Asia, and 44% in Sub-Saharan Africa. Of the 36,806 deaths after the neonatal period, 47% of deaths occurred in South Asia, 36% in sub-Saharan Africa, and 12% in Southeast Asia. Between 1990 and 2015, the global mortality rate due to neonatal tetanus dropped by 90% and that due to non-neonatal tetanus dropped by 81%. However, tetanus mortality rates were still high in a number of countries in 2015. The highest rates of neonatal tetanus mortality (more than 1,000 deaths per 100,000 population) were observed in Somalia, South Sudan, Afghanistan, and Kenya. The highest rates of mortality from tetanus after the neonatal period (more than 5 deaths per 100,000 population) were observed in Somalia, South Sudan, and Kenya.

conclusionsThough there have been tremendous strides globally in reducing the burden of tetanus, tens of thousands of unnecessary deaths from tetanus could be prevented each year by an already available inexpensive and effective vaccine. Availability of more high quality data could help narrow the uncertainty of tetanus mortality estimates.

Indexed as

InternationalityAdolescentAdultAfricaAgedAged, 80 and overAge FactorsAsiaAustralasiaCaribbean RegionChildChild, PreschoolEuropeFemaleGlobal Burden of DiseaseHumansDistributionMortalityTetanusTrends

Identifiers

PMID28178973
PMCPMC5299674
OpenAlexW2586707611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.