Evidence map›Paper›PMID 28178219›Full record

ArticleMolecules (Basel, Switzerland)2017

Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells.

Chunwa Jiang, Muqaddas Masood, Azhar Rasul, Wei Wei, Ya Wang, Muhammad Ali, Muhammad Mustaqeem, Jiang Li, Xiaomeng Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  5. Review
  6. Discovery of a Natural Product That Binds to theMolecules (Basel, Switzerland) · 2020
    Article
  7. Review
  8. Article
  9. Tetraspanin 1 inhibits TNFα-induced apoptosis via NF-κB signaling pathway in alveolar epithelial cells.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Chunwa JiangThe Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China. jiangcw833@nenu.edu.cn.
Muqaddas MasoodThe Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China. miss.nagra@yahoo.com.
Azhar RasulFaculty of Science and Technology, Government College University Faisalabad (GCUF), Faisalabad 38000, Pakistan. drazharrasul@gmail.com.
Wei WeiDental Hospital, Jilin University, Changchun 130021, China. drasharrasul@gmail.com.
Ya WangThe Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China. azcheena37@hotmail.com.
Muhammad AliFaculty of Science and Technology, Government College University Faisalabad (GCUF), Faisalabad 38000, Pakistan. alisam007@hotmail.com.
Muhammad MustaqeemDepartment of Chemistry, University of Sargodha, Sub-campus Bhakkar 30000, Pakistan. mustaqeem@uos.edu.pk.
Jiang LiDental Hospital, Jilin University, Changchun 130021, China. ljiang@jlu.edu.cn.
Xiaomeng LiThe Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China. lixm411@nenu.edu.cn.
Northeast Normal University · CNGovernment College University, Faisalabad · PKJilin University · CNUniversity of Sargodha · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Altholactone, a natural compound isolated from

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorFuransGoniothalamusHumansMaleNF-kappa BProstatic NeoplasmsPyronesReactive Oxygen SpeciesSignal TransductionSTAT3 Transcription FactoraltholactoneAntineoplastic Agents, PhytogenicFuransNF-kappa BPyronesReactive Oxygen SpeciesSTAT3 protein, humanSTAT3 Transcription Factoraltholactonenatural compoundNF-κBprostate cancerSTAT3

Identifiers

PMID28178219
PMCPMC6155856
OpenAlexW2586193505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.