ArticlePsychosomatic medicine2017
Early-Life Socioeconomic Disadvantage and Metabolic Health Disparities.
Article in Psychosomatic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic Status and Cardiovascular Responses to Standardized Stressors: A Systematic Review and Meta-Analysis.Psychosomatic medicine · 2018Pooled it
- Metabolic syndrome in youth with bipolar spectrum disorders treated with second-generation antipsychotics: baseline results from the community-based pragmatic MOBILITY Trial.European child & adolescent psychiatry · 2025Trial
- Prefrontal-medullary circuitry is necessary for sex-specific responses to metabolic stress in rats.Endocrinology · 2026Article
- Prefrontal-medullary circuitry is necessary for sex-specific responses to metabolic stress in rats.bioRxiv : the preprint server for biology · 2026Article
- Association between income, employment status, and asthma outcomes: a systematic review and meta-analysis.The Lancet regional health. Europe · 2025Article
- The Association of Cardiometabolic Risk Factors in Parent-Child Dyads in Guam: Pacific Islands Cohort on Cardiometabolic Health Study.International journal of environmental research and public health · 2025Article
- Metabolic Syndrome Indicators and Cardiovascular/Endocrine Risks in Rural Ecuador: A Cross-Sectional Study.Journal of personalized medicine · 2025Article
- Prevalence of metabolic syndrome among adults treated at a district hospital outpatient department.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Effects of multiple stress events at different stages of life on the incidence of metabolic syndrome.Frontiers in endocrinology · 2024Article
- Metabolic syndrome traits exhibit genotype-by-environment interaction in relation to socioeconomic status in the Mexican American family heart study.Frontiers in genetics · 2024Article
- Developmental Trajectory of Body Weight in Youths at Risk for Major Mood Disorders.JAMA network open · 2023Article
- Early life adversities and lifelong health outcomes: A review of the literature on large, social, long-lived nonhuman mammals.Neuroscience and biobehavioral reviews · 2023Review
- Metabolic health disparities driven by financial stress: Behavioural adaptation or modification?Stress and health : journal of the International Society for the Investigation of Stress · 2023Article
- Association between prenatal socioeconomic disadvantage, adverse birth outcomes, and inflammatory response at birth.Psychoneuroendocrinology · 2023Article
- Exploring disparities and novel insights into metabolic and cardiovascular comorbidities among COVID-19 patients in Mexico.Frontiers in public health · 2023Observational
- Poverty and inequality in real-world schizophrenia: a national study.Frontiers in public health · 2023Article
- Sex differences in autonomic responses to stress: implications for cardiometabolic physiology.American journal of physiology. Endocrinology and metabolism · 2022Review
- Socioeconomic disadvantage, chronic stress, and proinflammatory phenotype: an integrative data analysis across the lifecourse.PNAS nexus · 2022Article
- Evaluating the association between socioeconomic position and cardiometabolic risk markers in young adulthood by different life course models.BMC public health · 2022Article
- Personality traits at age 16 and risk of metabolic syndrome at age 46.Journal of psychosomatic research · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveA quarter of the world's population have metabolic syndrome (MetS). MetS prevalence is stratified by socioeconomic status (SES), such that low SES is associated with higher MetS risk. The present study examined the relative roles of early-life SES and current SES in explaining MetS risk.
methodsParticipants (N = 354; ages = 15-55 years, M [SD] = 36.5 [10.7] years; 55% female; 72.9% white, 16.9% Asian, 10.2% others) were evaluated for SES and MetS. All were in good health, defined as free of chronic medical illness and acute infectious disease. Using occupational status as a proxy for SES, we recruited roughly equal numbers of participants with low-low, low-high, high-low, and high-high combinations of early-life and current SES. We used the International Diabetes Federation definition for MetS using race- and sex-specific cutoffs for waist circumference, triglyceride levels, high-density lipoprotein cholesterol, blood pressure, and glycosylated hemoglobin levels.
resultsAnalyses revealed a main effect of low early-life SES on increased MetS risk according to the three separate definitions. They included the traditional MetS diagnosis (odds ratio [OR] = 1.53, confidence interval [CI] = 1.01-2.33, p = .044), the number of MetS components for which diagnostic thresholds were met (OR = 1.61, CI = 1.10-2.38, p = .015), and a continuous indicator of metabolic risk based on factor analysis (F(1,350) = 6.71, p = .010, partial η = .019). There was also a significant interaction of early-life SES and current SES in predicting MetS diagnosis (OR = 1.54, CI = 1.02-2.34). The main effects of current SES were nonsignificant in all analyses.
conclusionsThese findings suggest that MetS health disparities originate in childhood, which may be an opportune period for interventions.
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