Evidence map›Paper›PMID 28177987›Full record

ArticleDiseases of the colon and rectum2017

Quality of Life and Functional Outcome After Transanal Abdominal Transanal Proctectomy for Low Rectal Cancer.

John H Marks, Jean F Salem, Elsa B Valsdottir, Shadi S Yarandi, Gerald J Marks

Open access · greenAbstract readComparative Study
In one paragraph

Article in Diseases of the colon and rectum, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Assessment of Quality of Life in Patients with Colorectal Cancer in Kazakhstan.Asian Pacific journal of cancer prevention : APJCP · 2023
    Article
  2. Review
  3. Article
  4. Article
  5. Robotic Transanal Surgery for Rectal Cancer.Clinics in colon and rectal surgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

John H Marks1 Division of Colorectal Surgery, Lankenau Hospital, Wynnewood, Pennsylvania 2 Department of Surgery, University of Iceland, Reykjavik, Iceland.
Jean F Salem
Elsa B Valsdottir
Shadi S Yarandi
Gerald J Marks
Lankenau Medical Center · USUniversity of Iceland · IS

Funding

Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
NIDDK NIH HHS P30 DK089502
6 · The paper itself

Abstract

backgroundTransanal abdominal transanal proctectomy is a sphincter-preserving procedure designed to avoid colostomy in patients with cancer in the distal third of the rectum. Oncologic outcomes of this procedure have been established. However, data regarding patient satisfaction and quality of life are scant.

objectiveThe purpose of this study was to evaluate the quality of life and functional outcomes of patients after transanal abdominal transanal proctectomy.

designThis is a cross-sectional study. SETTINGS: The study was conducted at a tertiary referral colorectal center. PATIENTS: Patients who underwent transanal abdominal transanal proctectomy were included and surveyed using the Fecal Incontinence Quality of Life Scale, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30, the Quality of Life Questionnaire CR38 module, and a questionnaire designed by the authors to assess satisfaction with quality of life.

main outcome measuresQuality of life, functional outcomes, and patient satisfaction were measured and compared by age, tumor level, and stage of the disease.

resultsA total of 133 surveys were mailed, and 90 patients responded and were included in the study. Patient quality of life was not significantly different after surgery. Patients with more proximal tumors had better lifestyle, physical, and emotional scores. Older patients performed better on multiple levels, including coping, emotional, body image, future perspective, and digestive. Stage of disease had no impact on quality of life. Compared with reference values, patients who underwent transanal abdominal transanal proctectomy performed better on most of the components. All of patients preferred transanal abdominal transanal proctectomy over having a stoma based on their current anal sphincter function, and >97% of patients preferred transanal abdominal transanal proctectomy based on their current quality of life, sexual function, and level of activities. LIMITATIONS: This study is limited by the lack of a comparison group and a potential selection bias.

conclusionsSatisfaction with quality of life and functional outcomes is high after transanal abdominal transanal proctectomy. Older patients and those with more proximal tumors performed better. This patient population clearly preferred a sphincter-preserving option for treatment of their rectal cancer.

Indexed as

Quality of LifeAdultAgedAged, 80 and overColonic PouchesCross-Sectional StudiesFecal IncontinenceFemaleFollow-Up StudiesHumansLife StyleMaleMiddle AgedPatient SatisfactionPostoperative ComplicationsProctoscopy

Identifiers

PMID28177987
PMCPMC5881116
OpenAlexW2587995912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.