Trial reportApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2017
Impact of hot and cold exposure on human skeletal muscle gene expression.
Trial report in Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Review
- The combined influences of local heat application and resistance exercise on the acute mRNA response of skeletal muscle.Frontiers in physiology · 2024Article
- Cooling of male rat skeletal muscle during endurance-like contraction attenuates contraction-induced PGC-1α mRNA expression.Physiological reports · 2023Article
- The isolated effects of local cold application on proteolytic and myogenic signaling.Cryobiology · 2023Article
- The independent effects of local heat application on muscle growth program associated mRNA and protein phosphorylation.Journal of thermal biology · 2023Article
- Article
- No Mitochondrial Related Transcriptional Changes in Human Skeletal Muscle after Local Heat Application.International journal of environmental research and public health · 2022Article
- Influence of Local Muscle Cooling on Mitochondrial-Related Gene Expression at Rest.International journal of environmental research and public health · 2022Article
- Heat Acclimation in Females Does Not Limit Aerobic Exercise Training Outcomes.International journal of environmental research and public health · 2022Article
- Effect of local heat application during exercise on gene expression related to mitochondrial homeostasis.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021Article
- Effect of heat acclimation on metabolic adaptations induced by endurance training in soleus rat muscle.Physiological reports · 2021Article
- Effect of local cold application during exercise on gene expression related to mitochondrial homeostasis.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2021Article
- Short-Term Resistance Training Supported by Whole-Body Cryostimulation Induced a Decrease in Myostatin Concentration and an Increase in Isokinetic Muscle Strength.International journal of environmental research and public health · 2020Article
- Effects of exercise in a cold environment on gene expression for mitochondrial biogenesis and mitophagy.Cryobiology · 2019Article
- Effects of exercise in a cold environment on transcriptional control of PGC-1α.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Extreme Terrestrial Environments: Life in Thermal Stress and Hypoxia. A Narrative Review.Frontiers in physiology · 2018Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Many human diseases lead to a loss of skeletal muscle metabolic function and mass. Local and environmental temperature can modulate the exercise-stimulated response of several genes involved in mitochondrial biogenesis and skeletal muscle function in a human model. However, the impact of environmental temperature, independent of exercise, has not been addressed in a human model. Thus, the purpose of this study was to compare the effects of exposure to hot, cold, and room temperature conditions on skeletal muscle gene expression related to mitochondrial biogenesis and muscle mass. Recreationally trained male subjects (n = 12) had muscle biopsies taken from the vastus lateralis before and after 3 h of exposure to hot (33 °C), cold (7 °C), or room temperature (20 °C) conditions. Temperature had no effect on most of the genes related to mitochondrial biogenesis, myogenesis, or proteolysis (p > 0.05). Core temperature was significantly higher in hot and cold environments compared with room temperature (37.2 ± 0.1 °C, p = 0.001; 37.1 ± 0.1 °C, p = 0.013; 36.9 ± 0.1 °C, respectively). Whole-body oxygen consumption was also significantly higher in hot and cold compared with room temperature (0.38 ± 0.01 L·min
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.