ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2016
Head and neck reconstruction with pedicled flaps in the free flap era.
Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Incidence and influencing factors of surgical site infection in patients with oral cancer: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Free flap versus pedicled flap reconstruction in head and neck surgery: A systematic review and meta-analysis.JPRAS open · 2026Review
- The Submandibular-Facial Artery Perforator Flap (S-FAPF): A Novel Tool for Lower Face Reconstruction.Head & neck · 2026Article
- Personalized Strategies for Head and Neck Reconstruction Using Pedicled Flaps.Journal of personalized medicine · 2026Article
- Pedicled versus free flap reconstruction in head and neck surgery: analysis of complications and quality of life.BMC surgery · 2026Article
- One-stage tunneled de-epithelialized deltopectoral flap for huge head and neck cancer defects in the era of free flaps.Turkish journal of surgery · 2025Article
- Functional and Aesthetic Restoration After Surgical Treatment of Oral Squamous Cell Carcinoma Using Radial Forearm Free Flap: Case Report.Dentistry journal · 2025Article
- Free vs. Local Tissue Transfer and Reconstruction in Pediatric Head and Neck Cancer Patients: A Comparable Complication Outcome Review.Medicina (Kaunas, Lithuania) · 2025Article
- Review
- Surgical learning curve and flap survival in head and neck microvascular reconstruction using arterial and venous couplers.Contemporary oncology (Poznan, Poland) · 2025Article
- Local Flap Reconstructions in Oral Cavity Defects: An Insight from 104 Cases.Rambam Maimonides medical journal · 2024Article
- Oral Reconstruction with Locoregional Flaps after Cancer Ablation: A Systematic Review of the Literature.Journal of clinical medicine · 2024Review
- Molecular Genetic Analysis of Perioperative Colonization by Infection-Related Microorganisms in Patients Receiving Intraoral Microvascular Grafts.Journal of clinical medicine · 2024Article
- Application of supraclavicular island flap in oral and maxillofacial reconstruction.Oral and maxillofacial surgery · 2024Article
- Pedicled thoracoacromial artery compound flaps for circumferential hypopharyngeal reconstruction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- 10-Year Experience with the Modified Pectoralis Major Flap: The Use of the Deltopectoral Flap to Reduce Skin Tension.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Current Approaches to Salvage Surgery for Head and Neck Cancer: A Comprehensive Review.Cancers · 2023Review
- Matrix for Mucosal Regeneration in Transoral Glossectomy for Squamous Cell Carcinoma: Objective and Subjective Functional Evaluation.Current oncology (Toronto, Ont.) · 2023Article
- Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2022Article
- Postoperative Complications Associated with the Choice of Reconstruction in Head and Neck Cancer: An Outcome Analysis of 4,712 Patients from the ACS-NSQIP Database.Journal of reconstructive microsurgery · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nowadays, the transposition of microvascular free flaps is the most popular method for management of head and neck defects. However, not all patients are suitable candidates for free flap reconstruction. In addition, not every defect requires a free flap transfer to achieve good functional results. The aim of this study was to assess whether pedicled flap reconstruction of head and neck defects is inferior to microvascular free flap reconstruction in terms of complications, functionality and prognosis. The records of consecutive patients who underwent free flap or pedicled flap reconstruction after head and neck cancer ablation from 2006 to 2015, from a single surgeon, in the AOUC Hospital, Florence Italy were analysed. A total of 93 patients, the majority with oral cancer (n = 59), were included, of which 64 were pedicled flap reconstructions (69%). The results showed no significant differences in terms of functional outcome, flap necrosis and complications in each type of reconstruction. Multivariate regression analysis of flap necrosis and functional impairments showed no associated factors. Multivariate regression analysis of complicated flap healing showed that only comorbidities remained an explaining factor (p = 0.019). Survival analysis and proportional hazard regression analysis regarding cancer relapse or distant metastasis, showed no significant differences in prognosis of patients concerning both types of reconstruction. In this retrospective, non-randomised study cohort, pedicled flaps were not significantly inferior to free flaps for reconstruction of head and neck defects, considering functionality, complications and prognosis.
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