Evidence map›Paper›PMID 28177286›Full record

ArticleeLife2017

Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion.

Adriane G Otopalik, Marie L Goeritz, Alexander C Sutton, Ted Brookings, Cosmo Guerini, Eve Marder

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  7. Neuronal morphology enhances robustness to perturbations of channel densities.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Hacking brain development to test models of sensory coding.bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. From the Neuroscience of Individual Variability to Climate Change.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  11. The narrowing of dendrite branches across nodes follows a well-defined scaling law.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. TheFrontiers in neural circuits · 2021
    Review
  13. Article
  14. The Wiring Logic of an Identified Serotonergic Neuron That Spans Sensory Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  15. Article
  16. Article
  17. Robustness to Axon Initial Segment Variation Is Explained by Somatodendritic Excitability in Rat Substantia Nigra Dopaminergic Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adriane G OtopalikBiology Department and Volen Center, Brandeis University, Waltham, United States.ORCID 0000-0002-3224-6502
Marie L GoeritzBiology Department and Volen Center, Brandeis University, Waltham, United States.
Alexander C SuttonBiology Department and Volen Center, Brandeis University, Waltham, United States.
Ted BrookingsBiology Department and Volen Center, Brandeis University, Waltham, United States.
Cosmo GueriniBiology Department and Volen Center, Brandeis University, Waltham, United States.
Eve MarderBiology Department and Volen Center, Brandeis University, Waltham, United States.ORCID 0000-0001-9632-5448

Funding

Quantitative Neuroscience: Tools for Bridging Levels of AnalysisT32NS007292 · NINDS · BRANDEIS UNIVERSITY · PI GINA G TURRIGIANO · 1986 to 2026
$12.7M
Neuromodulation and Robustness of Neurons and NetworksR35NS097343 · NINDS · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 2017 to 2024
$7.8M
Neurotransmitter Modulation of Neuronal CircuitsR37NS017813 · NINDS · BRANDEIS UNIVERSITY · PI MARDER, EVE E · 2010 to 2016
$2.6M
Spatial mapping of receptor distributions on single identified neuronsF31NS092126 · NINDS · BRANDEIS UNIVERSITY · PI OTOPALIK, ADRIANE GERNDT · 2015 to 2016
$51k
NINDS NIH HHS F31 NS092126NINDS NIH HHS R35 NS097343NINDS NIH HHS R37 NS017813NINDS NIH HHS T32 NS007292
6 · The paper itself

Abstract

Neuronal physiology depends on a neuron's ion channel composition and unique morphology. Variable ion channel compositions can produce similar neuronal physiologies across animals. Less is known regarding the morphological precision required to produce reliable neuronal physiology. Theoretical studies suggest that moraphology is tightly tuned to minimize wiring and conduction delay of synaptic events. We utilize high-resolution confocal microscopy and custom computational tools to characterize the morphologies of four neuron types in the stomatogastric ganglion (STG) of the crab

Indexed as

MorphogenesisAnimalsComputer SimulationCrustaceaGanglia, AutonomicMicroscopy, ConfocalNeuronsCancer borealisdendritic treeneuronal morphologyneuroscienceoptimization principleswiring cost

Identifiers

PMID28177286
PMCPMC5323045

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.