Evidence map›Paper›PMID 28177237›Full record

ArticleJournal of the American Chemical Society2017

Direct C-H Cyanation of Arenes via Organic Photoredox Catalysis.

Joshua B McManus, David A Nicewicz

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Recent advances in [Nuclear medicine and biology · 2026
    Review
  2. Catalyst-Free Cyanation of Arenes by Acetonitrile in a Plasma-Liquid Microreactor.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  3. Nitrosonium Ion-Catalyzed Oxidative Chlorination of Arenes.The Journal of organic chemistry · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Enzymatic Cascades for Stereoselective and Regioselective Amide Bond Assembly.Angewandte Chemie (International ed. in English) · 2025
    Article
  10. Article
  11. Review
  12. One-Step Synthesis of [ACS central science · 2024
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Chem · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joshua B McManusDepartment of Chemistry, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-3290, United States.
David A NicewiczDepartment of Chemistry, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-3290, United States.ORCID 0000-0003-1199-9879

Funding

Catalytic Methods for Rapid Aromatic DerivatizationR01GM120186 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICEWICZ, DAVID A · 2016 to 2019
$1.1M
NIGMS NIH HHS R01 GM120186
6 · The paper itself

Abstract

Methods for the direct C-H functionalization of aromatic compounds are in demand for a variety of applications, including the synthesis of agrochemicals, pharmaceuticals, and materials. Herein, we disclose the construction of aromatic nitriles via direct C-H functionalization using an acridinium photoredox catalyst and trimethylsilyl cyanide under an aerobic atmosphere. The reaction proceeds at room temperature under mild conditions and has proven to be compatible with a variety of electron-donating and -withdrawing groups, halogens, and nitrogen- and oxygen-containing heterocycles, as well as aromatic-containing pharmaceutical agents.

Indexed as

AcridinesCalixarenesCatalysisMolecular StructureNitrilesOxidation-ReductionPhotochemical ProcessesTemperatureAcridinesCalixarenesNitriles

Identifiers

PMID28177237
PMCPMC5541851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.