Evidence map›Paper›PMID 28176965›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2017

RE-PERG, a new procedure for electrophysiologic diagnosis of glaucoma that may improve PERG specificity.

Alberto Mavilio, Dario Sisto, Paolo Ferreri, Nicola Cardascia, Giovanni Alessio

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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  8. RE-PERG, a new paradigm for glaucoma diagnosis, in myopic eyes.Clinical ophthalmology (Auckland, N.Z.) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alberto MavilioSocial Health District, Glaucoma Center, Azienda Sanitaria Locale, Brindisi.
Dario SistoDepartment of Ophthalmology and Otolaryngology, University of Bari, Bari, Italy.
Paolo FerreriDepartment of Ophthalmology and Otolaryngology, University of Bari, Bari, Italy.
Nicola CardasciaDepartment of Ophthalmology and Otolaryngology, University of Bari, Bari, Italy.
Giovanni AlessioDepartment of Ophthalmology and Otolaryngology, University of Bari, Bari, Italy.
University of Bari Aldo Moro · ITASL Roma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA significant variability of the second harmonic (2ndH) phase of steady-state pattern electroretinogram (SS-PERG) in intrasession retest has been recently described in glaucoma patients (GP), which has not been found in healthy subjects. To evaluate the reliability of phase variability in retest (a procedure called RE-PERG or REPERG) in the presence of cataract, which is known to affect standard PERG, we tested this procedure in GP, normal controls (NC), and cataract patients (CP).

methodsThe procedure was performed on 50 GP, 35 NC, and 27 CP. All subjects were examined with RE-PERG and SS-PERG and also with spectral domain optical coherence tomography and standard automated perimetry. Standard deviation of phase and amplitude value of 2ndH were correlated by means of one-way analysis of variance and Pearson correlation, with the mean deviation and pattern standard deviation assessed by standard automated perimetry and retinal nerve fiber layer and the ganglion cell complex thickness assessed by spectral domain optical coherence tomography. Receiver operating characteristics were calculated in cohort populations with and without cataract.

resultsStandard deviation of phase of 2ndH was significantly higher in GP with respect to NC (

conclusionRE-PERG may improve the specificity of SS-PERG in clinical practice in the discrimination of GP.

Indexed as

ganglion cellsglaucomaoptical coherence tomographypattern electroretinogramvisual field

Identifiers

PMID28176965
PMCPMC5271393
OpenAlexW2581546765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.