ArticleInternational journal of nanomedicine2017
Bioglass implant-coating interactions in synthetic physiological fluids with varying degrees of biomimicry.
Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Modification of titanium orthopedic implants with bioactive glass: a systematic review ofFrontiers in bioengineering and biotechnology · 2023Pooled it
- Engineering a biomimetic multiphasic suture anchor system for enhanced rotator cuff enthesis regeneration.Science advances · 2026Article
- Engineering a Biomimetic Multiphasic Suture Anchor System for Enhanced Rotator Cuff Enthesis Regeneration.bioRxiv : the preprint server for biology · 2025Article
- Controlling Plasma-Functionalized Fillers for Enhanced Properties of PLA/ZnO Biocomposites: Effects of Excess l-Lactic Acid and Biomedical Implications.ACS applied materials & interfaces · 2025Article
- Analysis of bioglass/cerium dioxide nanocoating and its antibacterial properties for the restoration of hard tissue around oral titanium implants.American journal of translational research · 2025Article
- Two decades of continuous progresses and breakthroughs in the field of bioactive ceramics and glasses driven by CICECO-hub scientists.Bioactive materials · 2024Review
- Biocompatible Composite Filaments Printable by Fused Deposition Modelling Technique: Selection of Tuning Parameters by Influence of Biogenic Hydroxyapatite and Graphene Nanoplatelets Ratios.Biomimetics (Basel, Switzerland) · 2024Article
- Microcrystallization Effects in Borosilicate Bioactive Glasses: Controllable Release of Bioactive Elements and In Vitro Degradation Properties.Materials (Basel, Switzerland) · 2023Article
- Hydroxyapatite Thin Films of Marine Origin as Sustainable Candidates for Dental Implants.Pharmaceutics · 2023Article
- Modulated Laser Cladding of Implant-Type Coatings by Bovine-Bone-Derived Hydroxyapatite Powder Injection on Ti6Al4V Substrates-Part I: Fabrication and Physico-Chemical Characterization.Materials (Basel, Switzerland) · 2022Article
- Influence of Ceramic Particles Size and Ratio on Surface-Volume Features of the Naturally Derived HA-Reinforced Filaments for Biomedical Applications.Journal of functional biomaterials · 2022Article
- Electrochemical and In Vitro Biological Evaluation of Bio-Active Coatings Deposited by Magnetron Sputtering onto Biocompatible Mg-0.8Ca Alloy.Materials (Basel, Switzerland) · 2022Article
- New solutions for combatting implant bacterial infection based on silver nano-dispersed and gallium incorporated phosphate bioactive glass sputtered films: A preliminary study.Bioactive materials · 2022Article
- In vitro Evaluation of a 20% Bioglass-Containing 3D printable PLA Composite for Bone Tissue Engineering.International journal of bioprinting · 2022Article
- Influence of Composition and Preparation Conditions on the Structure and Properties of Composite Materials TiOACS omega · 2021Article
- Sol-Gel Synthesis and Characterization of a Quaternary Bioglass for Bone Regeneration and Tissue Engineering.Materials (Basel, Switzerland) · 2021Article
- Preliminary Studies on Graphene-Reinforced 3D Products Obtained by the One-Stage Sacrificial Template Method for Bone Reconstruction Applications.Journal of functional biomaterials · 2021Article
- Fish Bone Derived Bi-Phasic Calcium Phosphate Coatings Fabricated by Pulsed Laser Deposition for Biomedical Applications.Marine drugs · 2020Article
- Preparation of CaO@TiOACS omega · 2020Article
- Amorphous Silicon Oxynitrophosphide-Coated Implants Boost Angiogenic Activity of Endothelial Cells.Tissue engineering. Part A · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic physiological fluids are currently used as a first in vitro bioactivity assessment for bone grafts. Our understanding about the interactions taking place at the fluid-implant interface has evolved remarkably during the last decade, and does not comply with the traditional International Organization for Standardization/final draft International Standard 23317 protocol in purely inorganic simulated body fluid. The advances in our knowledge point to the need of a true paradigm shift toward testing physiological fluids with enhanced biomimicry and a better understanding of the materials' structure-dissolution behavior. This will contribute to "upgrade" our vision of entire cascades of events taking place at the implant surfaces upon immersion in the testing media or after implantation. Starting from an osteoinductive bioglass composition with the ability to alleviate the oxidative stress, thin bioglass films with different degrees of polymerization were deposited onto titanium substrates. Their biomineralization activity in simulated body fluid and in a series of new inorganic-organic media with increasing biomimicry that more closely simulated the human intercellular environment was compared. A comprehensive range of advanced characterization tools (scanning electron microscopy; grazing-incidence X-ray diffraction; Fourier-transform infrared, micro-Raman, energy-dispersive, X-ray photoelectron, and surface-enhanced laser desorption/ionization time-of-flight mass spectroscopies; and cytocompatibility assays using mesenchymal stem cells) were used. The information gathered is very useful to biologists, biophysicists, clinicians, and material scientists with special interest in teaching and research. By combining all the analyses, we propose herein a step forward toward establishing an improved unified protocol for testing the bioactivity of implant materials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.