Evidence map›Paper›PMID 28176877›Full record

ArticleScientific reports2017

Structural white matter and functional connectivity alterations in patients with shoulder apprehension.

Davide Zanchi, Gregory Cunningham, Alexandre Lädermann, Mehmet Ozturk, Pierre Hoffmeyer, Sven Haller

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Gut-brain axis in health and brain disease.Chinese medical journal · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Davide ZanchiDepartment of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Gregory CunninghamDivision of Orthopaedic and Trauma Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland.
Alexandre LädermannDivision of Orthopaedic and Trauma Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland.
Mehmet OzturkDivision of Orthopaedic and Trauma Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland.
Pierre HoffmeyerDivision of Orthopaedic and Trauma Surgery, Department of Surgery, University Hospitals of Geneva, Switzerland.
Sven HallerFaculty of Medicine of the University of Geneva, Switzerland.
University Hospital of Geneva · CHUniversity of Basel · CHUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous functional magnetic resonance imaging (fMRI) findings indicate that shoulder apprehension is more complex than a pure mechanical problem of the shoulder, showing a direct modification in functional brain networks associated with motor inhibition and emotional regulation. The current study extends these findings by investigating further structural alterations in patients with shoulder apprehension compared to controls. 14 aged patients with shoulder apprehension (27.3 ± 2.0 years) and 10 matched healthy controls (29.6 ± 1.3 years) underwent clinical and fMRI examination including fMRI and diffusion tensor imaging (DTI). Tract-based spatial statistics procedure was used to analyze white matter (WM) alterations. Functional images were analyzed investigating resting state network connectivity. DTI results were correlated with different shoulder clinical scores and functional connectivity networks. Fractional anisotropy (FA), representing white matter integrity, is increased in the left internal capsule and partially in the thalamus in patients compared to controls. Moreover, FA correlates negatively with simple shoulder test (SST) scores (p < .05) and positively with a functional connectivity network qualitatively replicating previous results (p < .01). This study extends previous findings, showing that in addition to functional changes, structural white matter changes are also present in patients with shoulder apprehension.

Indexed as

AdultCase-Control StudiesDemographyDiffusion Tensor ImagingHumansMagnetic Resonance ImagingMaleNerve NetShoulderWhite Matter

Identifiers

PMID28176877
PMCPMC5296739
OpenAlexW2586275077

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.