ArticleScientific reports2017
Comparative study of the gut microbiome potentially related to milk protein in Murrah buffaloes (Bubalus bubalis) and Chinese Holstein cattle.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 57 citations in OpenAlex.
- Comparative Analysis of Bovine Fecal Microbiota and Short-Chain Fatty Acids Variation During Dry Period, Pregnancy and Lactation.Microorganisms · 2026Article
- Dietary Bacillus subtilis modulates rumen epithelial barrier function and immune responses in weaned Hu sheep.Scientific reports · 2026Article
- Metagenomic Applications to Herbivore Gut Microbiomes: A Comprehensive Review of Microbial Diversity and Host Interactions.Animals : an open access journal from MDPI · 2025Review
- Multi-omics reveal the gut microbiota-mediated severe foraging environment adaption of small wild ruminants in the Three-River-Source National Park, China.Integrative zoology · 2025Article
- Gut microbiome and diet contribute to ecological niche differentiation between argali (Ovis ammon hodgsoni) and blue sheep (Pseudois nayaur) on the Qinghai-Tibet Plateau.Communications biology · 2025Article
- Gastrointestinal Microorganisms and Blood Metabolites in Holstein Calves with Different Heat Stress Responses in the Same Hot Environment.Microorganisms · 2025Article
- Analysis of the fecal microbiome and metabolome in dairy cows with different body condition scores.PloS one · 2025Article
- Changes in Gut Microbiota in Peruvian Cattle Genetic Nucleus by Breed and Correlations with Beef Quality.Veterinary sciences · 2024Article
- Regulation of Milk Fat Synthesis: Key Genes and Microbial Functions.Microorganisms · 2024Review
- Hydrolyzed milk infant formula effectively protects against milk protein allergy: Independent of whey protein source.Food science & nutrition · 2024Article
- Characterization of bovine vaginal microbiota using 16S rRNA sequencing: associations with host fertility, longevity, health, and production.Scientific reports · 2024Article
- Comparative Study of Bacterial Microbiota Differences in the Rumen and Feces of Xinjiang Brown and Holstein Cattle.Animals : an open access journal from MDPI · 2024Article
- The microbiome of the buffalo digestive tract.Nature communications · 2022Article
- Effects of a multi-strain probiotic on growth, health, and fecal bacterial flora of neonatal dairy calves.Animal bioscience · 2022Article
- Article
- Review
- Herbivore camping reshapes the taxonomy, function and network of pasture soil microbial communities.PeerJ · 2022Article
- Effects of whole maize high-grain diet feeding on colonic fermentation and bacterial community in weaned lambs.Frontiers in microbiology · 2022Article
- Gut microbiome colonization and development in neonatal ruminants: Strategies, prospects, and opportunities.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Review
- LiveAnimals : an open access journal from MDPI · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies suggested a close relationship between ruminant gut microbes and the mammary gland. In this study, shotgun metagenomic sequencing was used to reveal the differences in the intestinal microbiome potentially related to milk components in Murrah buffaloes and Chinese Holstein cattle. A PCoA based on the weighted Unifrac distances showed an apparent clustering pattern in the structure of intestinal microbiota between buffalo and cattle. We could attribute the structural difference to the genera of Sutterella, Coprococcus and Dorea. A further analysis of microbial functional features revealed that the biosynthesis of amino acids (including lysine, valine, leucine and isoleucine), lipopolysaccharide biosynthesis and cofactor/vitamin biosynthesis were enriched in the buffalo. In contrast, dairy cattle had higher levels of pyruvate metabolism and carbon fixation in photosynthetic organisms. A further correlation analysis based on different milk components and the typical microbiome uncovered a significant positive correlation between milk protein and the microbial biosynthesis of amino acids, which was also positively correlated in the genera of Parabacteroides, Dorea and Sutterella. This study will expand our understanding of the intestinal microbiome of buffalo and cattle as representative ruminants, as well as provide new views about how to improve the production and nutritional qualities of animal milk.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.